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- Title
Attenuation of free radicals by an aqueous extract of peels of safed muslitubers (Chlorophytum borivilianum Sant et Fernand).
- Authors
Kaur, Rajinder; Thukral, A. K.; Arora, Saroj
- Abstract
Safed musli (Chlorophyturm borivilianum Sant et Fernand) is one of the most important medicinal herb the roots of which after peeling are widely used as a natural sex tonic and thereafter peels are discarded as waste. So, in the present investigation an attempt has been made to check the antioxidative potential of aqueous ex- tract of peels of sated musli tubers employing various in vitro assays, such as 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging, deoxyribose degradation, reducing power, ferrous ion chelation and lipid peroxidation. It was observed that the scavenging activity of aqueous extract was dose dependent in all the assays. The extract showed strong inhibitory activity towards lipid peroxidation of rat liver homogenate induced by the FeCl2-H2O2 system, in both site and non-site specific deoxyribose degradation assays as well as in DPPH free radical scavenging as- says. On the contrary, the effect was comparatively less in reducing power and ferrous ion chelation assays. The results obtained in the in vitro assays clearly established the antioxidant potency of aqueous extract of peels of sated musli tubers. In view of this observation it is suggested that sated musli peels could also be effectively used as an ingredient in the health supplements to alleviate oxidative stress. However, convincing evidences for the free radical scavenging activity of peels of sated musli are needed to ascertain the in vivo safety of such extracts.
- Subjects
HERBAL medicine; FREE radical reactions; ANTIOXIDANTS; IRON chelates; PEROXIDATION; DEOXYRIBOSE; OXIDATIVE stress; DIETARY supplements; USEFUL plants; PREVENTION
- Publication
Journal of Chinese Clinical Medicine, 2010, Vol 5, Issue 1, p7
- ISSN
1562-9023
- Publication type
Article