We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Intraocular Pressure Changes after Different Types of Intravitreal Injections for the Treatment of Macular Edema.
- Authors
YAZICI, Ahmet Taylan; ALAGÖZ, Cengiz; ALAGÖZ, Neşe; DÜNDAR, Hüseyin; BOZKURT, Ercüment; ÇAKIR, Mehmet; YILMAZ, Ömer Faruk
- Abstract
Purpose: To evaluate the effects of intravitreal triamcinolone acetonide (IVTA), bevacizumab (IVB), and the combination of IVTA/IVB on the intraocular pressure (IOP) change in a 6-month follow-up period. Materials and Methods: Two hundred and seven eyes of 194 consecutive patients (113 male, mean age 61±10 years) that received an intravitreal injection between January 2007 and January 2008 for the treatment of macular edema were evaluated retrospectively. Group 1 consisted of 100 eyes of 94 patients treated with 4 mg IVTA injection, Group 2 consisted of 32 eyes of 27 patients treated with 1.25 mg IVB, and Group 3 consisted of 75 eyes of 73 patients treated with a combination of 2 mg TA and 1.25 mg bevacizumab. The primary outcome measures of the study were change in IOP and the number of eyes with elevated IOP requiring glaucoma treatment. Results: The initial IOP was similar in all groups (p=0.413). However, in all follow-up examinations the difference between the groups was significant (p value for all visits <0.05). Treatment for elevated IOP was required in 21% eyes following IVTA injection and in 4% eyes following IVTA/IVB injection (p=0.001). None of the eyes that received IVB required glaucoma treatment. IOP rise was highest at one month following IVTA injection and at one week following IVTA/IVB injection. Conclusion: A significant relation between the steroid dose and IOP elevation was found. Reduction of steroid dose resulted in less frequent IOP elevation.
- Subjects
RETINAL diseases; TREATMENT of eye diseases; INTRAOCULAR pressure; INJECTIONS; BEVACIZUMAB; TRIAMCINOLONE acetonide; FOLLOW-up studies (Medicine); COMBINATION drug therapy; STEROID drugs
- Publication
Retina-Vitreus/Journal of Retina-Vitreous, 2011, Vol 19, Issue 2, p117
- ISSN
1300-1256
- Publication type
Article