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- Title
Malformations of cortical development.
- Authors
Desikan, Rahul S.; Barkovich, A. James
- Abstract
Malformations of cortical development (MCDs) compose a diverse range of disorders that are common causes of neurodevelopmental delay and epilepsy. With improved imaging and genetic methodologies, the underlying molecular and pathobiological characteristics of several MCDs have been recently elucidated. In this review, we discuss genetic and molecular alterations that disrupt normal cortical development, with emphasis on recent discoveries, and provide detailed radiological features of the most common and important MCDs. Ann Neurol 2016;80:797-810.
- Publication
Annals of Neurology, 2016, Vol 80, Issue 6, p797
- ISSN
0364-5134
- Publication type
journal article
- DOI
10.1002/ana.24793