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- Title
Wound sepsis after low risk elective cholecystectomy: The effect of cefuroxime.
- Authors
Morran, C. G.; Thomson, G.; White, A.; McNaught, W.; Smith, D. C.; McArdle, C. S.
- Abstract
A prospective randomized double-blind study was performed to assess the value of a single intravenous injection of 1.5 g cefuroxime in the prevention of wound sepsis after low risk elective cholecystectomy. Wound infection developed in 10 of 81 control patients compared with 2 of 79 treated patients (P<0.05). Wound sepsis occurred more commonly in patients with infected bile or with a positive culture from a closing wound swab. Cefuroxime significantly reduced the isolation of staphylococci but not other organisms from the closing wound swab and also produced a significant reduction in wound infection in patients with sterile bile.
- Publication
British Journal of Surgery, 1984, Vol 71, Issue 7, p540
- ISSN
0007-1323
- Publication type
Article
- DOI
10.1002/bjs.1800710724