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Molecular events involved in transcriptional activation of heat shock genes become progressively refractory to heat stimulation during aging of human diploid fibroblasts.
- Published in:
- Journal of Cellular Physiology, 1991, v. 149, n. 3, p. 560, doi. 10.1002/jcp.1041490327
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- Publication type:
- Article
Emerging Role of SMILE in Liver Metabolism.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2907, doi. 10.3390/ijms24032907
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- Publication type:
- Article
An Inverse Agonist GSK5182 Increases Protein Stability of the Orphan Nuclear Receptor ERRγ via Inhibition of Ubiquitination.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 96, doi. 10.3390/ijms24010096
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- Publication type:
- Article
SMILE Downregulation during Melanogenesis Induces MITF Transcription in B16F10 Cells.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15094, doi. 10.3390/ijms232315094
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- Article
Hepatocyte DAX1 Deletion Exacerbates Inflammatory Liver Injury by Inducing the Recruitment of CD4 + and CD8 + T Cells through NF-κB p65 Signaling Pathway in Mice.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14009, doi. 10.3390/ijms232214009
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- Article
Melatonin Regulates Iron Homeostasis by Inducing Hepcidin Expression in Hepatocytes.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3593, doi. 10.3390/ijms23073593
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- Publication type:
- Article
Orphan Nuclear Receptor ERRγ Is a Transcriptional Regulator of CB1 Receptor-Mediated TFR2 Gene Expression in Hepatocytes.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 6021, doi. 10.3390/ijms22116021
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- Publication type:
- Article
Orphan Nuclear Receptor ERRγ Is a Novel Transcriptional Regulator of IL-6 Mediated Hepatic BMP6 Gene Expression in Mice.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7148, doi. 10.3390/ijms21197148
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- Publication type:
- Article
Orphan nuclear receptor oestrogen-related receptor γ (ERR<sub>γ</sub>) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression.
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- Biochemical Journal, 2015, v. 470, n. 2, p. 181, doi. 10.1042/BJ20141494
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- Publication type:
- Article
An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ.
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- Nucleic Acids Research, 2018, v. 46, n. 22, p. 12192, doi. 10.1093/nar/gky1145
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- Publication type:
- Article
RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure.
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- Nucleic Acids Research, 2016, v. 44, n. 3, p. 1095, doi. 10.1093/nar/gkv1034
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- Publication type:
- Article
Transcriptional cross talk between orphan nuclear receptor ERRγ and transmembrane transcription factor ATF6α coordinates endoplasmic reticulum stress response.
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- Nucleic Acids Research, 2013, v. 41, n. 14, p. 6960, doi. 10.1093/nar/gkt429
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- Publication type:
- Article
Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation.
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- Nucleic Acids Research, 2010, v. 38, n. 14, p. 4607, doi. 10.1093/nar/gkq227
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- Publication type:
- Article
Molecular characterization of SMILE as a novel corepressor of nuclear receptors.
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- Nucleic Acids Research, 2009, v. 37, n. 12, p. 4100, doi. 10.1093/nar/gkp333
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- Publication type:
- Article
The Orphan Nuclear Receptor SHP Is a Positive Regulator of Osteoblastic Bone Formation.
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- Journal of Bone & Mineral Research, 2010, v. 25, n. 2, p. 262, doi. 10.1359/jbmr.090718
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- Publication type:
- Article
Foxa2 and Nurr1 Synergistically Yield A9 Nigral Dopamine Neurons Exhibiting Improved Differentiation, Function, and Cell Survival.
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- Stem Cells, 2010, v. 28, n. 3, p. 501, doi. 10.1002/stem.294
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- Publication type:
- Article
PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis.
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- Diabetologia, 2014, v. 57, n. 12, p. 2576, doi. 10.1007/s00125-014-3366-x
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- Publication type:
- Article
Orphan nuclear receptor SHP regulates iron metabolism through inhibition of BMP6-mediated hepcidin expression.
- Published in:
- Scientific Reports, 2016, p. 34630, doi. 10.1038/srep34630
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- Publication type:
- Article
Metformin stimulates IGFBP-2 gene expression through PPARalpha in diabetic states.
- Published in:
- Scientific Reports, 2016, p. 23665, doi. 10.1038/srep23665
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- Publication type:
- Article
Corrigendum: Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation.
- Published in:
- Scientific Reports, 2016, p. 18552, doi. 10.1038/srep18552
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- Publication type:
- Article
Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation.
- Published in:
- Scientific Reports, 2015, p. 16577, doi. 10.1038/srep16577
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- Publication type:
- Article
Chenodeoxycholic Acid Reduces Hypoxia Inducible Factor-1α Protein and Its Target Genes.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130911
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- Publication type:
- Article
Treatment with 4-Methylpyrazole Modulated Stellate Cells and Natural Killer Cells and Ameliorated Liver Fibrosis in Mice.
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- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0127946
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- Publication type:
- Article
Transforming Growth Factor-β1 Signaling Represses Testicular Steroidogenesis through Cross-Talk with Orphan Nuclear Receptor Nur77.
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- PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104812
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- Publication type:
- Article
Orphan Nuclear Receptor Errγ Induces C-Reactive Protein Gene Expression through Induction of ER-Bound Bzip Transmembrane Transcription Factor CREBH.
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- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086342
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- Publication type:
- Article
Hepatic Cannabinoid Receptor Type 1 Mediates Alcohol-Induced Regulation of Bile Acid Enzyme Genes Expression Via CREBH.
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- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068845
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- Publication type:
- Article
Small Heterodimer Partner-Targeting Therapy Inhibits Systemic Inflammatory Responses through Mitochondrial Uncoupling Protein 2
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063435
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- Publication type:
- Article
Hypoxia Induces PDK4 Gene Expression through Induction of the Orphan Nuclear Receptor ERRγ.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046324
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- Publication type:
- Article
The Estrogen-Related Receptor Alpha Upregulates Secretin Expressions in Response to Hypertonicity and Angiotensin II Stimulation.
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- PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039913
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- Publication type:
- Article
Lipocalin2 Induced by Bacterial Flagellin Protects Mice against Cyclophosphamide Mediated Neutropenic Sepsis.
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- Microorganisms, 2020, v. 8, n. 5, p. 646, doi. 10.3390/microorganisms8050646
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- Publication type:
- Article
An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ.
- Published in:
- Nucleic Acids Research, 2005, v. 33, n. 21, p. 6756, doi. 10.1093/nar/gki976
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- Publication type:
- Article
Synergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix–loop–helix protein E2A and orphan nuclear receptor SF‐1.
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- Nucleic Acids Research, 2003, v. 31, n. 23, p. 6860, doi. 10.1093/nar/gkg906
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- Publication type:
- Article
Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer.
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- 2018
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- Publication type:
- journal article
The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors.
- Published in:
- Nature Immunology, 2011, v. 12, n. 8, p. 742, doi. 10.1038/ni.2064
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- Article
Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome.
- Published in:
- Nature Communications, 2015, v. 6, n. 2, p. 6115, doi. 10.1038/ncomms7115
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- Publication type:
- Article
Corrigendum: The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.
- Published in:
- Nature Communications, 2015, v. 6, n. 1, p. 6076, doi. 10.1038/ncomms7076
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- Publication type:
- Article
The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.
- Published in:
- Nature Communications, 2014, v. 5, n. 7, p. 4410, doi. 10.1038/ncomms5410
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- Publication type:
- Article
Estrogen-related receptor gamma regulates dopaminergic neuronal phenotype by activating GSK3β/ NFAT signaling in SH- SY5Y cells.
- Published in:
- Journal of Neurochemistry, 2015, v. 133, n. 4, p. 544, doi. 10.1111/jnc.13085
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- Publication type:
- Article
eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet.
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- Nutrition & Metabolism, 2017, v. 14, p. 1, doi. 10.1186/s12986-017-0202-6
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- Publication type:
- Article
Epigallocatechin-3-Gallate Suppresses BMP-6-Mediated SMAD1/5/8 Transactivation of Hepcidin Gene by Inducing SMILE in Hepatocytes.
- Published in:
- Antioxidants, 2021, v. 10, n. 10, p. 1590, doi. 10.3390/antiox10101590
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- Publication type:
- Article
Epigallocatechin-3-Gallate (EGCG)-Inducible SMILE Inhibits STAT3-Mediated Hepcidin Gene Expression.
- Published in:
- Antioxidants, 2020, v. 9, n. 6, p. 514, doi. 10.3390/antiox9060514
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- Publication type:
- Article
The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression.
- Published in:
- PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0159425
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- Publication type:
- Article
Frontline Science: Estrogen‐related receptor γ increases poly(I:C)‐mediated type I IFN expression in mouse macrophages.
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- Journal of Leukocyte Biology, 2021, v. 109, n. 5, p. 865, doi. 10.1002/JLB.2HI1219-762R
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- Publication type:
- Article
Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase--Dependent Regulation of the Orphan Nuclear Receptor SHP.
- Published in:
- Diabetes, 2008, v. 57, n. 2, p. 306, doi. 10.2337/db07-0381
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- Publication type:
- Article
Glucotoxicity in the INS-1 Rat Insulinoma Cell Line Is Mediated by the Orphan Nuclear Receptor Small Heterodimer Partner.
- Published in:
- Diabetes, 2007, v. 56, n. 2, p. 431, doi. 10.2337/db06-0753
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- Publication type:
- Article
Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl<sub>4</sub>-induced acute liver injury.
- Published in:
- Archives of Toxicology, 2021, v. 95, n. 9, p. 3071, doi. 10.1007/s00204-021-03112-1
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- Publication type:
- Article
An inverse agonist of estrogen-related receptor γ regulates 2-arachidonoylglycerol synthesis by modulating diacylglycerol lipase expression in alcohol-intoxicated mice.
- Published in:
- Archives of Toxicology, 2020, v. 94, n. 2, p. 427, doi. 10.1007/s00204-019-02648-7
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- Publication type:
- Article
Hepatocyte CREBH deficiency aggravates inflammatory liver injury following chemokine-dependent neutrophil infiltration through upregulation of NF-κB p65 in mice.
- Published in:
- Archives of Toxicology, 2020, v. 94, n. 2, p. 509, doi. 10.1007/s00204-019-02633-0
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- Publication type:
- Article
Inverse agonist of ERRγ reduces cannabinoid receptor type 1-mediated induction of fibrinogen synthesis in mice with a high-fat diet-intoxicated liver.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 9, p. 2885, doi. 10.1007/s00204-018-2270-4
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- Publication type:
- Article
Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45β-dependent manner.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 8, p. 2563, doi. 10.1007/s00204-018-2247-3
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- Publication type:
- Article