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- Title
Synthesis of Cyano-pyrrolo[1,2- a][1,10]phenanthroline Derivatives Using a Multicomponent Condensation.
- Authors
Marandi, Ghasem; Hazeri, Nourallah; Maghsoodlou, Malek T.; Habibi ‐ Khorassani, Sayyed M.; Torbati, Niloufar Akbarzadeh; Rostami ‐ Charati, Faramarz; Skelton, Brian W.; Makha, Mohamed
- Abstract
1,10-Phenanthroline reacts with malonitrile and aldehydes in the presence of isocyanides as domino-Knoevenagel-nucleophilic cycloaddition for generation of a new class of 10-(aryl)-11-(alkyl- or arylamino-)pyrrolo[1,2- a][1,10]phenanthroline-9-carbonitrile compounds in excellent yield. All compounds are fully characterized with one structurally authenticated by a single X-ray diffraction study.
- Subjects
CYANIDES synthesis; PHENANTHROLINE derivatives; CONDENSATION reactions; ISOCYANIDES; NUCLEOPHILIC addition (Chemistry); RING formation (Chemistry); ALDEHYDES; CARBONITRILES
- Publication
Journal of Heterocyclic Chemistry, 2013, Vol 50, Issue 3, p568
- ISSN
0022-152X
- Publication type
Article
- DOI
10.1002/jhet.1532