We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Synthese neuer Aryl-(3,-dichloro-4-pyridazinly)-ketone und ihre Reaktion mit N,N-Dinucleophilen.
- Authors
Eichhorn, Thomas A.; Piesch, Steffen; Ried, Walter
- Abstract
Synthesis of New Aryl (3,6-Dichloro-4-pyridazinyl) Ketones and their Reaction with N,N-Dinucleophiles The synthesis of the new aryl (3,6-dichloro-4-pyridazinyl) ketones 3a-e vïa Friedel- Crafts acylation of the aromatic compounds 2a-e with 3,6-dichloro-4-pyridazincarbonyl chloride (1) is described. The ketones 3a-e cyclized with N,N-dinucleophilic reagents to the 3-aryl-5-chloro-l H -pyrazolo[3,4- c]pyridazines 4a-d, and 3a-c are converted into the 3-aryl-5-chloro-l H -pyrazolo[3,4- c]pyridazin - l -ethanols 5a-c and to the hitherto unknown ring system of the 5-aryl-3-chloro-7,8-dihydro-9 H -pyridazino[3,4- e][1,4]diazepines ( 6a-c).
- Publication
Helvetica Chimica Acta, 1988, Vol 71, Issue 5, p988
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.19880710507