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- Title
In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions.
- Authors
Chiang, Jeremy Chung Bo; Roy, Maitreyee; Kim, Juno; Markoulli, Maria; Krishnan, Arun V.
- Abstract
In-vivo corneal confocal microscopy is a powerful imaging technique which provides clinicians and researcher with the capabilities to observe microstructures at the ocular surfaces in significant detail. In this Mini Review, the optics and image analysis methods with the use of corneal confocal microscopy are discussed. While novel insights of neuroanatomy and biology of the eyes, particularly the ocular surface, have been provided by corneal confocal microscopy, some debatable elements observed using this technique remain and these are explored in this Mini Review. Potential improvements in imaging methodology and instrumentation are also suggested. This Mini Review provides a focus on corneal confocal microscopy and insights into the neuroanatomy of the corneal surface using this technique and open debates are highlighted.
- Subjects
CONFOCAL microscopy; IMAGE analysis; CORNEA; NEUROANATOMY
- Publication
Communications Biology, 2023, Vol 6, Issue 1, p1
- ISSN
2399-3642
- Publication type
Article
- DOI
10.1038/s42003-023-05005-8