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- Title
Cognitive impairment associated with psychosis (CIAPS): Validity of clinical criteria to detect cognitive impairment.
- Authors
Sánchez-Torres, A.; Gil-Berrozpe, G.; Lorente-Omeñaca, R.; Zandio, M.; Moreno-Izco, L.; Janda, L.; Peralta, D.; Peralta, V.; Cuesta, M.
- Abstract
Introduction: Even though cognitive impairment is considered a hallmark of schizophrenia, it has not been included as a criterion into major diagnostic systems. Objectives: To test whether a set of clinical-defined cognitive impairment criteria can have utility in the assessment of psychosis patients in clinical practice. Methods: We assessed 98 patients with a psychotic disorder, diagnosed using DSM 5 criteria. We developed a set of cognitive impairment associated with psychosis (CIAPs) criteria following the format of current DSMcriteria and based on previous literature. The CIAPs criteria include: A) criterion for evidence of cognitive impairment after the beginning of illness; B) cognitive impairment clinically evidenced, affecting functioning in everyday activities in at least two out of six cognitive domains; C) and D) exclusion criterion for either delirium or other neurocognitive disorders, respectively, as causal agents of the cognitive impairment. The psychosis patients dichotomized by the CIAPs criteria were tested regarding the neuropsychological performance in attention, speed of processing, verbal memory, visual memory, working memory, executive function and social cognition tasks. Also a Global Cognitive Index was calculated. Results: Forty-three patients with psychosis fulfilled the CIAPs criteria (43.9%). MANOVA profile analyses revealed a pattern of statistically significant deficits in all the cognitive dimensions except for social cognition in CIAPs+ patients regarding CIAPS-, with prominent deficits in processing speed and memory functions. Conclusions: The CIAPs criteria could be an auxiliary method for clinicians to assess cognitive impairment. It may also permit clinical estimation of the influence of cognitive deficits on the ecological functioning of patients.
- Subjects
COGNITION disorders; PSYCHOSES; DELIRIUM; VERBAL memory; VISUAL memory; EXECUTIVE function
- Publication
European Psychiatry, 2021, Vol 64, pS519
- ISSN
0924-9338
- Publication type
Article
- DOI
10.1192/j.eurpsy.2021.1390