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- Title
Successful treatment of thrombotic microangiopathy associated with dengue infection: A case report and literature review.
- Authors
Nieto‐Ríos, John Fredy; Álvarez Barreneche, María Fernanda; Penagos, Sara Catalina; Bello Márquez, Diana Carolina; Serna‐Higuita, Lina Maria; Ramírez Sánchez, Isabel Cristina
- Abstract
Abstract: Dengue infection has been associated with multiple renal complications, including glomerulonephritis, acute tubular necrosis, tubulointerstitial nephritis, and thrombotic microangiopathy (TMA), this last one being a rare complication of dengue, with only a few reported cases. TMA associated with dengue can be explained by an alteration in the activity of the enzyme ADAMTS13, leading to thrombotic thrombocytopenic purpura; or it can be secondary to direct or indirect endothelial injury by the virus, which leads to hemolytic uremic syndrome. Here, we present a case of severe TMA, not related to ADAMTS13, which was clearly associated with dengue infection.
- Subjects
THROMBOTIC thrombocytopenic purpura treatment; DENGUE; THROMBOTIC microangiopathies; PLASMA exchange (Therapeutics); ROTAVIRUSES; DISEASE risk factors
- Publication
Transplant Infectious Disease, 2018, Vol 20, Issue 1, p1
- ISSN
1398-2273
- Publication type
Case Study
- DOI
10.1111/tid.12824