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- Title
Comparison of duration of post operative analgesia using 0.25% ropivacaine with dexamethasone vs 0.25% ropivacaine with clonidine in patients undergoing total abdominal hysterectomy using ultrasound guided transversus abdominis plane block.
- Authors
D., Saranya; S., Lakshmi Krishna; Kulasekar, Ashok
- Abstract
Background: Our study aims to the compare the duration of post-operative analgesia, times of post-operative opioid consumption, post-operative sedation score, and haemodynamic changes between the groups on using 8mg Dexamethasone and 75 µgm clonidine as an adjuvant to 0.25% Ropivacaine in ultrasound-guided bilateral TAP block in patients undergoing total abdominal hysterectomy. Study design: Prospective, randomized, double blinded study with 56 patients were included and allocated using a -generated randomization code into: Group A (n=28 patients): Received USG guided bilateral TAP block with Injection Ropivacaine (0.5%) 20ml + Dexamethasone (8 mg) 2ml + Normal Saline 18 ml and Group B (n=28 patients) Received USG guided bilateral TAP block with Injection Ropivacaine (0.5%) 20ml + clonidine (75mcgs) 0.5 ml + Normal Saline 19.5 ml. Results: The duration of pain relief was highest (14.3 ± 4.7 hours) in group B patients compared to group A (11.1 ± 5.1 hours). The duration of analgesia provided by 75 mcg clonidine was statistically significant (p<0.001). Post-operative opioid consumption was higher in group A compared to group B which is statistically not significant. (P>0.05). There was also no significant difference in between the study groups for sedation scoring and haemodynamic changes. Conclusion: The addition of dexamethasone 8mg or clonidine 75 mcgs to 0.25% ropivacaine significantly prolongs the duration of analgesia and reduces postoperative opioids requirement, thereby facilitating early recovery and ambulation. On comparing, clonidine appears to be superior adjunct, in terms of pain relief.
- Subjects
HYSTERO-oophorectomy; TRANSVERSUS abdominis muscle; CLONIDINE; ROPIVACAINE; ANALGESIA; VAGINAL hysterectomy; DEXAMETHASONE
- Publication
European Journal of Cardiovascular Medicine, 2024, Vol 14, Issue 2, p1194
- ISSN
2042-4884
- Publication type
Article