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- Title
Utilization of Anti-Thyroid Peroxidase Antibody in Local Clinics and Hospitals and Intraindividual Changes in Korean Patients.
- Authors
Rihwa Choi; Sukjung Lee; Sang Gon Lee; Eun Hee Lee
- Abstract
Background: Limited data are available for test utilization and intraindividual changes in anti-thyroid peroxidase antibodies (anti-TPO Ab) in Korean patients. Methods: Using a laboratory information system, we retrospectively investigated longitudinally measured anti-TPO Ab along with thyroid function test (TFT) in Korean patients visiting local clinics. Results: During the two-year study period, 542 test results from 183 Korean patients were requested from 51 local clinics and hospitals. Among all 183 patients, 94 (51.4%) exhibited positive anti-TPO Ab (> 34 IU/mL) at initial measurement. Among them, 13.8% (13/94) changed to negative anti-TPO Ab at least once during follow-up. Among 89 patients with initial negative anti-TPO Ab result, five (5.6%) changed to positive anti-TPO Ab at least once during follow up. Conclusions: Some patients exhibited qualitative changes in anti-TPO Ab. Future studies are needed to clarify the clinical implication of such changes.
- Subjects
SOUTH Korea; KOREANS; THYROID gland function tests; IMMUNOGLOBULINS; THYROTROPIN receptors; PEROXIDASE
- Publication
Clinical Laboratory, 2021, Issue 9, p2152
- ISSN
1433-6510
- Publication type
Article
- DOI
10.7754/Clin.Lab.2021.201227