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- Title
Alkyl Aryl Ether Bond Formation with PhenoFluor.
- Authors
Xiao Shen; Neumann, Constanze N.; Kleinlein, Claudia; Goldberg, Nathaniel W.; Ritter, Tobias
- Abstract
An alkyl aryl ether bond formation reaction between phenols and primary and secondary alcohols with PhenoFluor has been developed. The reaction features a broad substrate scope and tolerates many functional groups, and substrates that are challenging for more conventional ether bond forming processes may be coupled. A preliminary mechanistic study indicates reactivity distinct from conventional ether bond formation.
- Subjects
BOND formation mechanism; PHENOLS; FUNCTIONAL groups; ALCOHOL; REACTIVITY (Chemistry); BIOCHEMICAL substrates
- Publication
Angewandte Chemie International Edition, 2015, Vol 54, Issue 19, p5662
- ISSN
1433-7851
- Publication type
Article
- DOI
10.1002/anie.201500902