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- Title
The relation between coronary artery disease and newly diagnosed dysglycemia.
- Authors
Truong, Cam Dinh; Ton, Tung Thanh
- Abstract
Introduction: There is a known association between hyperglycemia and the presence of coronary syndrome. The purpose of this work is to study risk factors and clinical manifestations of hyperglycemia in patients diagnosed with coronary artery disease. Methods: The study was conducted in 2018–2020 among 505 patients in Ho Chi Minh city, Vietnam. Based on the results of the glucose test at 0 and 120 min, the patients were divided into the groups: with normal glucose metabolism (control, 204), patients with impaired fasting glucose levels (175 patients, group 2), and patients with impaired glucose tolerance, including diabetes mellitus (126, group 3). Anthropometric measurements were performed, and the levels of hemoglobin HbA, glucose, lipids were measured. Results: In the group of patients with fasting hyperinsulinemia, all variables (body weight, body mass index, waist circumference, LAP, creatinine clearance) differed considerably as compared to the control group (p ≤ 0.0001). Decrease in tissue sensitivity to insulin is already present at normal levels of glucose metabolism. Conclusions: The study found that diabetes mellitus and prediabetes are more typical for patients with metabolic syndrome and acute coronary syndrome. The results obtained will allow predicting the risk of developing coronary syndrome depending on the presence of diabetes mellitus or prediabetes.
- Subjects
VIETNAM; GLYCOSYLATED hemoglobin; C-reactive protein; OBESITY; HDL cholesterol; TRIGLYCERIDES; CARDIOVASCULAR diseases risk factors; HYPERGLYCEMIA; BODY weight; HIGH performance liquid chromatography; CARBOHYDRATE metabolism; ANTHROPOMETRY; SODIUM; GLYCEMIC control; BLOOD sugar; DIABETES; HYPERINSULINISM; ACUTE coronary syndrome; FISHER exact test; MANN Whitney U Test; DISEASE incidence; CASE-control method; RISK assessment; INSULIN; COMPARATIVE studies; INSULIN sensitivity; IMMUNOASSAY; HYPERLIPIDEMIA; WAIST-hip ratio; CORONARY artery disease; WAIST circumference; METABOLIC syndrome; DESCRIPTIVE statistics; DISEASE prevalence; METROPOLITAN areas; GLUCOSE tolerance tests; BODY mass index; ANALYTICAL chemistry techniques; DATA analysis software; PREDIABETIC state; LIPIDS; C-peptide; INSULIN resistance; CHOLESTEROL; CREATININE; DISEASE risk factors; SYMPTOMS
- Publication
Perfusion, 2023, Vol 38, Issue 7, p1428
- ISSN
0267-6591
- Publication type
Article
- DOI
10.1177/02676591221113970