We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Escherichia coli single-strand binding protein stabilizes specific denatured sites in superhelical DNA.
- Authors
Glikin, Gerardo C.; Gargiulo, Giuseppe; Rena-Descalzi, Liliana; Worcel, Abraham
- Abstract
Escherichia coli single-strand binding protein relaxes super coiled DNA molecules containing the Drosophila melanogaster histone gene repeat unit, by stabilizing denaturation bubbles that map near the boundaries of the genes, at sites that in native chromatin have been shown to be hypersensitive to nucleases. A similar process may contribute to the propagation of such hypersensitive sites after their induction on the activation of gene expression.
- Publication
Nature, 1983, Vol 303, Issue 5920, p770
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/303770a0