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- Title
Two New Anti-Tobacco Mosaic Virus Isoindolin-1-Ones from the Leaves of Nicotiana tabacum.
- Authors
Xu, Li; Zhou, Tao; Zhang, Jian-Duo; Deng, Le-Le; Jiang, Jia-Rui; Yang, Wen-Wu; Liu, Chun-Bo; Kong, Wei-Song; Li, Xue-Mei; Yang, Guang-Yu; Hu, Qiu-Fen; Liu, Xin
- Abstract
Two new isoindolin-1-ones, 6-(3-hydroxypropyl)-2,4-dimethylisoindolin-1-one (1) and 4-(hydroxymethyl)-6-(3-hydroxypropyl)-2-methylisoindolin-1-one (2), were isolated from the leaves of Nicotiana tabacum. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds 1 and 2 exhibited high anti-TMV activities with inhibition rates of 42.3 and 46.2% at the concentration of 20 μM, respectively.
- Subjects
TOBACCO; MOSAIC viruses; SCHISANDRA; HYDROXYMETHYL compounds; NICOTIANA
- Publication
Chemistry of Natural Compounds, 2021, Vol 57, Issue 6, p1047
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-021-03547-z