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- Title
Determination of left ventricular long-axis orientation using MRI: changes during the respiratory and cardiac cycles in normal and diseased subjects.
- Authors
Foster, John E.; Engblom, Henrik; Martin, Thomas N.; Wagner, Galen S.; Steedman, Tracey; Ferrua, Stefania; Elliott, Alex T.; Dargie, Henry J.; Groenning, Bjoern A.
- Abstract
It has previously been shown that magnetic resonance imaging (MRI) can be used to accurately determine left ventricular (LV) long-axis orientation in healthy individuals. However, the inter- and intra-observer variability in patients with acute coronary syndrome (ACS) and chronic heart failure (CHF) has not been explored. Furthermore, the changes in LV long-axis orientation because of respiration and during the cardiac cycle remain to be determined. LV long-axis orientation was determined by MRI in the frontal and transverse planes in 44 subjects with no cardiac disease, 20 ACS patients and 13 CHF patients. Changes in LV long-axis orientation because of respiration were assessed in a subset of 25 subjects. Changes during the cardiac cycle were assessed in six subjects from each subject group. Reproducibility was assessed by a re-examination of 17 subjects after 28 days. The inter- and intra-observer variability for LV long-axis orientation was low for all subject groups. The difference between the baseline and the 28 days examinations was −1·4 ± 5·9° and −0·8 ± 4·4° in the frontal and transverse planes, respectively. No significant change in LV long-axis orientation was found between end-expiration and end-inspiration (frontal plane, P = 0·63 and transverse plane, P = 0·42; n = 25). No significant difference in change of the LV long-axis orientation during the cardiac cycle was found between the subject groups (frontal plane, chi-square 1·8, P = 0·40 and transverse plane, chi-square 5·7, P = 0·06). There is a low inter-and intra-observer variability and a high reproducibility for determining LV long-axis orientation in patients with no cardiac disease as well as in patients with ACS or CHF. There is no significant change in LV long-axis orientation due to respiration, and only small changes during the cardiac cycle in these groups.
- Subjects
MAGNETIC resonance imaging; LEFT heart ventricle; HEART beat; RESPIRATION; VITAL signs; DIAGNOSTIC imaging
- Publication
Clinical Physiology & Functional Imaging, 2005, Vol 25, Issue 5, p286
- ISSN
1475-0961
- Publication type
Article
- DOI
10.1111/j.1475-097X.2005.00624.x