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- Title
Quality of life in Serbian patients with Parkinson's disease.
- Authors
Ziropada L; Stefanova E; Potrebic A; Kostic VS; Ziropada, Ljubomir; Stefanova, Elka; Potrebić, Aleksandra; Kostić, Vladimir S
- Abstract
<bold>Background: </bold>The Parkinson's Disease Questionnaire (PDQ-39) is a well-validated British scale for the assessment of health-related quality of life (QoL) in Parkinson's disease (PD).<bold>Objective: </bold>To validate the Serbian version of the PDQ-39, while also providing additional information on the characteristics of this instrument.<bold>Patient and Methods: </bold>A total of 102 Serbian PD patients were asked to complete the PDQ-39, a disease-specific QoL questionnaire, as well as the generic, health status questionnaire (SF-36-version 1), and the 21-item Beck Depression Inventory. Neurological examination included the Hoehn and Yahr staging, Unified Parkinson's disease rating scale (UPDRS)-part III, Schwab and England scale, and the Mini-Mental State Examination.<bold>Results: </bold>Internal consistency analysis yielded a Cronbach's alpha of 0.83. Cronbach's alpha was above 0.70 for seven out of eight subscales (range from 0.73 to 0.91). A hierarchical structure of the PDQ-39 was revealed, with one global higher-order factor and two lower-order factors. The strongest predictor of the QoL in PD was the presence of depression, while motor disability (UPDRS-part III score) additionally contributed to poor QoL. Cognitive impairment has not been correlated with poor QoL. Also, QoL measures were not different between young- (< or =50 years) and older-onset PD patients.<bold>Conclusions: </bold>The PDQ-39 is a reliable and valid instrument for the assessment of QoL in Serbian PD patients.
- Publication
Quality of Life Research, 2009, Vol 18, Issue 7, p833
- ISSN
0962-9343
- Publication type
journal article
- DOI
10.1007/s11136-009-9500-4