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- Title
Antiproliferative Activity Evaluation of a Series of N-1,3-Benzothiazol-2-ylbenzamides as Novel Apoptosis Inducers.
- Authors
Corbo, Filomena; Carocci, Alessia; Armenise, Domenico; De Laurentis, Nicolino; Laghezza, Antonio; Loiodice, Fulvio; Ancona, Patrizia; Muraglia, Marilena; Pagliarulo, Vincenzo; Franchini, Carlo; Catalano, Alessia
- Abstract
A series of N-1,3-benzothiazol-2-ylbenzamide derivatives were studied for their antiproliferative activity on human liver hepatocellular carcinoma (HepG2) and human breast cancer (MCF-7) cell lines. Most of them were found to show a prominent inhibitory effect on cell growth. Among the most active compounds, 1k emerged for its proapoptotic effect that is particularly evident towards MCF-7 cancer cell lines.
- Subjects
BENZOTHIAZOLE; BENZAMIDE; APOPTOSIS; LIVER cancer; CHEMICAL derivatives; CANCER cell growth
- Publication
Journal of Chemistry, 2016, p1
- ISSN
2090-9063
- Publication type
Article
- DOI
10.1155/2016/4267564