We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
CircOMA1 promotes tumour growth and metastasis of bladder cancer by modulating IGF‐IR/MAPK/EMT pathway.
- Authors
Zhang, Lianghao; Zhan, Yonghao; Li, Longqing; Deng, Haotian; Wang, Jiange; Zhu, Zhaowei; Zhang, Xuepei
- Abstract
CircOMA1 promotes tumour growth and metastasis of bladder cancer by modulating IGF-IR/MAPK/EMT pathway Figure S3 (A) The results of qRT-PCR showed that circOMA1 negatively regulates the expression of miR-145-5p in BC cells in vitro. Although the prognostic results of patients with early-stage bladder cancer (BC) are very high, the 5-year survival rates of patients in advanced stages are greatly reduced to less than 6%.1,2 Thus, effective prognostic and therapeutic target biomarkers for early BC diagnostics are urgently needed. (D) The Western blotting showed the changes in bladder cancer (BC) cells protein levels of IGF-IR/MAPK/EMT markers.
- Subjects
CIRCULAR RNA; BLADDER cancer; INSULIN-like growth factor receptors; SOMATOMEDIN C; METASTASIS; EXOSOMES
- Publication
Clinical & Translational Medicine, 2022, Vol 12, Issue 8, p1
- ISSN
2001-1326
- Publication type
Article
- DOI
10.1002/ctm2.983