We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Serum and urinary biomarkers of collagen type‐I turnover predict prognosis in patients with heart failure.
- Authors
He, Tianlin; Melgarejo, Jesus D.; Clark, Andrew L.; Yu, Yu‐Ling; Thijs, Lutgarde; Díez, Javier; López, Begoña; González, Arantxa; Cleland, John G.; Schanstra, Joost P.; Vlahou, Antonia; Latosinska, Agnieszka; Mischak, Harald; Staessen, Jan A.; Zhang, Zhen‐Yu; Jankowski, Vera
- Abstract
Serum and urinary biomarkers of collagen type-I turnover predict prognosis in patients with heart failure Dear Editor, Previous studies indicated an association of biomarkers reflecting collagen turnover with heart failure.1,2 However, their value in predicting unfavorable outcomes is unknown. For serum samples, we used ELISA Kit to quantify the collagen synthesis biomarkers carboxy-terminal propeptide of procollagen type I (PICP),8 collagen degradation biomarkers carboxy-terminal telopeptide of collagen type I (CITP),9 and matrix metalloproteinase (MMP-1)10, which are known as good indicators of collagen turnover (Figure S1).
- Subjects
HEART failure patients; COLLAGEN; NEPRILYSIN
- Publication
Clinical & Translational Medicine, 2021, Vol 11, Issue 1, p1
- ISSN
2001-1326
- Publication type
Article
- DOI
10.1002/ctm2.267