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- Title
Efficacy of Acitretin for Porokeratosis in a Child with Chronic Cutaneous Graft Versus Host Disease.
- Authors
Borroni, Riccardo G.; Poddighe, Dimitri; Zecca, Marco; Brazzelli, Valeria
- Abstract
Porokeratosis is a rare disorder of epidermal keratinization that is regarded as a precancerous. Recipients of hematopoietic stem cell transplantation (HSCT) have a greater risk of skin cancer; chronic graft versus host disease (GVHD) is an additional risk factor. A 16-year-old boy who had received HSCT for acute myelogenous leukemia was referred to us for sclerodermoid chronic cutaneous GVHD. Two years later, he developed disseminated porokeratosis with a few atypical lesions. Despite cryotherapy, numerous lesions of porokeratosis recurred rapidly. Acitretin resulted in good clinical response and reduced the rate of onset of new lesions.
- Subjects
GRAFT versus host disease; KERATINIZATION; HEMATOPOIETIC stem cell transplantation; ACUTE myeloid leukemia; COLD therapy; PRECANCEROUS conditions
- Publication
Pediatric Dermatology, 2013, Vol 30, Issue 1, p148
- ISSN
0736-8046
- Publication type
Article
- DOI
10.1111/j.1525-1470.2011.01610.x