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- Title
Skin Zinc Concentrations in Patients with Varicose Ulcers.
- Authors
Ackerman, Zvi; Loewenthal, Ella; Seidenbaum, Moshe; Rubinow, Alan; Gorodetsky, Raphael
- Abstract
<em>The concentration of zinc in the skin has been determined noninvasively in patients with varicose vein ulcers. The examinations were performed with the use of diagnostic x-ray spectrometry, a method based on x-ray fluorescence for</em> in vivo <em>noninvasive evaluation of trace elements. Four skin foci were examined: at the periphery of the ulcer and control areas in a nonulcerated area in the diseased leg, in the noninvolved leg, and in the proximal inner surface of the arm. Zinc levels around the ulcer (mean ± SD, 9.8 ± 4.0 μg of zinc in 1 g of wet tissue) were higher than those in the nonulcerated skin in the diseased leg (6.9 ± 3.0 μg/g, p> 0.05) and those in the noninvolved leg (5.4 ± 2.0 μg/g, p <0.01). The concentration of zinc in the inner proximal surface of the arm (9.8 ± 2.8 μg/g) was significantly higher than those of a control group (5.3 ± 1.9 μg/g, p <0.01). These results suggest a defect of zinc distribution in patients with varicose vein ulcers</em>.
- Subjects
VARICOSE veins; ULCERS; VEIN diseases; SKIN; ZINC; X-ray spectroscopy
- Publication
International Journal of Dermatology, 1990, Vol 29, Issue 5, p360
- ISSN
0011-9059
- Publication type
Article
- DOI
10.1111/j.1365-4362.1990.tb04763.x