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- Title
Gastric Fluid Calprotectin Levels.
- Authors
Çikot, Murat; Gemici, Eyüp
- Abstract
Objective: This study aims toprove the presence of calprotectin in gastric fluid, and to evaluate the use of gastric fluid calprotectin in the diagnosis of gastric cancer. Materials and Methods: Included in this prospective study were 60 patients with upper gastrointestinal system complaints. Gastric fluid samples obtained during gastroscopy procedures through an ERCP cannula were stored at -20 degrees centigrade for six months, after which the calprotectin levels were measured. Standard endoscopic biopsies were also taken from the patients included in the study for tissue diagnosis. Results: A statistically significant difference was found between the groups (p=0.0001), with significant differences identified between the three groups. The p values identified in comparisons of group 1 and group 2; group 1 and group 3; and group 2 and group 3 were found to be p=0.043, p=0.001 and p=0.0001. Conclusion: Calprotectin, which is found in the gastric fluid, may be used in the differential diagnosis of benign and malignant ulcers. Prospective studies are needed to support the use of calprotectin in early diagnoses of gastric cancer.
- Subjects
ANTIGEN analysis; STOMACH tumors; BIOPSY; GASTRIC juice; GASTROSCOPY; LONGITUDINAL method; TUMOR markers; ENDOSCOPIC gastrointestinal surgery; DIAGNOSIS
- Publication
Medical Journal of Bakirkoy, 2018, Vol 14, Issue 4, p433
- ISSN
1305-9319
- Publication type
Article
- DOI
10.4274/BTDMJB.20180705093950