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- Title
Cereal bar sweetened with stevia leaves reduces fatty liver in diabetic rats.
- Authors
Beserra da Silva, Sandra; Marcelly Martins, Luana; Piovan, Silvano; Milan, Paula Gimenez; Gonçalves da Costa Silva, João Paulo; Vicente Seixas, Flávio Augusto; Edna Mareze-Costa, Cecília; Cláudio da Costa, Silvio
- Abstract
Diabetes mellitus and hepatic steatosis are diseases of great epidemiological impact and have been associated with increased consumption of sugary foods and drinks. The objective of this work was to evaluate the effect of food supplementation with cereal bars sweetened with Stevia rebaudiana leaves pretreated with ethanol (SLPE) on the metabolic control of streptozotocin-induced diabetic rats. Two cereal bar formulations were developed: one sweetened with SLPE, and the other sweetened with sucrose. The cereal bars were added to the standard ration for rodents (125g:1000g) and offered ad libitum to diabetic animals for 30 days. Important physiological parameters were recorded during and at the end of this period for metabolic control (body weight, food intake, glycemia, fructosamine, triglycerides, cholesterol, AST, ALT, liver fat and glucose tolerance). The diet supplemented with cereal bars sweetened with SLPE significantly reduced the amount of liver fat in diabetic rats, suggesting the potential of cereal bars sweetened with SLPE to act as a functional food for diabetic patients.
- Subjects
BARS (Desserts); FATTY liver; PEOPLE with diabetes; STREPTOZOTOCIN; METABOLIC regulation; STEVIA rebaudiana; FUNCTIONAL foods; SOFT drinks
- Publication
Brazilian Journal of Agricultural Sciences / Revista Brasileira de Ciências Agrárias, 2020, Vol 15, Issue 4, p1
- ISSN
1981-1160
- Publication type
Article
- DOI
10.5039/agraria.v15i4a8688