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- Title
Occurrence and Properties of Thiosilvatins.
- Authors
Salvatore, Maria Michela; Nicoletti, Rosario; DellaGreca, Marina; Andolfi, Anna
- Abstract
The spread of studies on biodiversity in different environmental contexts is particularly fruitful for natural product discovery, with the finding of novel secondary metabolites and structural models, which are sometimes specific to certain organisms. Within the large class of the epipolythiodioxopiperazines, which are typical of fungi, thiosilvatins represent a homogeneous family that, so far, has been reported in low frequency in both marine and terrestrial contexts. However, recent observations indicate that these compounds have been possibly neglected in the metabolomic characterization of fungi, particularly from marine sources. Aspects concerning occurrence, bioactivities, structural, and biosynthetic properties of thiosilvatins are reviewed in this paper.
- Subjects
METABOLITES; STRUCTURAL models; NATURAL products; FUNGI
- Publication
Marine Drugs, 2019, Vol 17, Issue 12, p664
- ISSN
1660-3397
- Publication type
Article
- DOI
10.3390/md17120664