We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Fan the flame: trazodone-induced mania in a unipolar depressed patient with stable sertraline treatment.
- Authors
Jianbo Hu; Jianbo Lai; Hanzhi Zheng; Shaohua Hu; Yi Xu
- Abstract
Depressed patients often complain of sleep disturbance. Routine antidepressive strategies sometimes fail to deal with this intractable issue. Indeed, the supplementation of sleep promoting antidepressants (eg, trazodone, mirtazapine, and agomelatine) is prevalent in clinical practice. However, the combination of different antidepressants may increase the affective lability. Herein, we document a patient with unipolar depression who was compliant with sertraline treatment and who dramatically switched to mania after adding trazodone as a sleeping aid. This case extended our understanding of the potential manic-switching risk when trazodone is used to promote sleep.
- Subjects
TRAZODONE; ANTIDEPRESSANTS; SERTRALINE; MENTAL depression; AFFECTIVE disorders; SLEEP substances
- Publication
Neuropsychiatric Disease & Treatment, 2017, Vol 13, p2251
- ISSN
1176-6328
- Publication type
Article
- DOI
10.2147/NDT.S143965