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Lower Locus Coeruleus Integrity Signals Elevated Entorhinal Tau and Clinical Progression in Asymptomatic Older Individuals.
Published in:
Annals of Neurology, 2024, v. 96, n. 4, p. 650, doi. 10.1002/ana.27022
By:
- Engels‐Domínguez, Nina;
- Riphagen, Joost M.;
- Van Egroo, Maxime;
- Koops, Elouise A.;
- Smegal, Lindsay F.;
- Becker, J. Alex;
- Prokopiou, Prokopis C.;
- Bueichekú, Elisenda;
- Kwong, Kenneth K.;
- Rentz, Dorene M.;
- Salat, David H.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Increasing the Diagnostic Accuracy of Medial Temporal Lobe Atrophy in Alzheimer's Disease.
Published in:
Journal of Alzheimer's Disease, 2011, v. 25, n. 3, p. 477, doi. 10.3233/JAD-2011-102043
By:
- Jacobs, Heidi I.L.;
- Van Boxtel, Martin P.J.;
- van der Elst, Wim;
- Burgmans, Saartje;
- Smeets, Floortje;
- Gronenschild, Ed H.B.M.;
- Verhey, Frans R.J.;
- Uylings, Harry B.M.;
- Jolles, Jelle
Publication type:
Article
Using 7T MRI to study hippocampal structures in Alzheimer's disease and post‐SARS‐CoV2 infection.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083216
By:
- Hosseini, Akram A.;
- Adeyemi, Oluwatobi F;
- Bowtell, Richard;
- Penny, Gowland;
- Ibrahim, Tamer;
- Liou, Jr‐Jiun;
- Santini, Tales;
- Li, Jinghang;
- Alkateeb, Salem;
- Habes, Mohamad;
- Goss, Monica;
- Vahidy, Farhaan S;
- Jacobs, Heidi I.L.;
- Girard, Timothy D.;
- de Erausquin, Gabriel A.;
- Snyder, Heather M;
- Seshadri, Sudha
Publication type:
Article
Covid‐19 may have a detrimental impact on sensorimotor function.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083191
By:
- Goss, Monica;
- Bernal, Rebecca;
- Patel, Vibhuti N;
- Li, Karl;
- Garbarino, Valentina R.;
- Nair, Rejani R;
- Snyder, Heather M;
- de Erausquin, Gabriel A.;
- Ganguli, Mary;
- Snitz, Beth E.;
- Girard, Timothy D.;
- Jacobs, Heidi I.L.;
- Hosseini, Akram A.;
- Ibrahim, Tamer;
- Vahidy, Farhaan S;
- Satizabal, Claudia L.;
- Himali, Jayandra Jung;
- Seshadri, Sudha
Publication type:
Article
Spatial Extent as a more sensitive amyloid biomarker for early stages of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083164
By:
- Farrell, Michelle E.;
- Thibault, Emma G.;
- Becker, Alex;
- Price, Julie C;
- Schultz, Aaron P.;
- Properzi, Michael J;
- Buckley, Rachel F.;
- Jacobs, Heidi I.L.;
- Hanseeuw, Bernard J;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Defining and characterizing neocortical tau resistance in preclinical Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083125
By:
- Properzi, Michael J;
- Townsend, Diana;
- Klinger, Hannah M;
- Boyle, Rory;
- Coughlan, Gillian T;
- Hanseeuw, Bernard J;
- Amariglio, Rebecca E.;
- Rentz, Dorene M.;
- Jacobs, Heidi I.L.;
- Price, Julie C;
- Chhatwal, Jasmeer P.;
- Schultz, Aaron P.;
- Hohman, Timothy J.;
- Donohue, Michael C.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Buckley, Rachel F.
Publication type:
Article
Associations of 24‐h rest‐activity patterns with plasma markers of neurodegeneration and Alzheimer's disease pathology in cognitively unimpaired individuals.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082960
By:
- Van Egroo, Maxime;
- Beckers, Elise;
- Ashton, Nicholas J.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Jacobs, Heidi I.L.
Publication type:
Article
Locus coeruleus microstructural integrity is linked to plasma GFAP concentration and Aβ<sub>42/40</sub> ratio in cognitively unimpaired individuals: a 7T MRI study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082969
By:
- Patsyuk, Yuliya;
- Van Egroo, Maxime;
- van Hooren, Roy W.E.;
- Ashton, Nicholas J.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Poser, Benedikt A;
- Jacobs, Heidi I.L.
Publication type:
Article
Relationship between norepinephrine metabolism and plasma markers of tau pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082789
By:
- Beckers, Elise;
- Riphagen, Joost M.;
- Ashton, Nicholas J.;
- Janelidze, Shorena;
- Blennow, Kaj;
- Hansson, Oskar;
- Zetterberg, Henrik;
- Jacobs, Heidi I.L.;
- Van Egroo, Maxime
Publication type:
Article
Preliminary validation of the Stress and Adversity Inventory for Adults (Adult STRAIN) in Dutch and its associations with in‐vivo locus coeruleus integrity.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082786
By:
- Engels, Nina;
- Riphagen, Joost M.;
- Van Egroo, Maxime;
- Spahr, Chandler M.;
- Slavich, George M;
- Jacobs, Heidi I.L.
Publication type:
Article
Disparities in Research Participation within a Multi‐Racial SARS‐CoV‐2 Cohort for Evaluation of Ultrahigh Field (7T) MRI and Clinical Precursors of Alzheimer's Disease and Related Dementias.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 22, p. 1, doi. 10.1002/alz.077318
By:
- Vahidy, Farhaan S;
- Hosseini, Akram A.;
- Girard, Timothy D.;
- Ibrahim, Tamer;
- Jacobs, Heidi I.L.;
- Roman, Gustavo C;
- Masdeu, Joseph C.;
- Li, Karl;
- Garbarino, Valentina R.;
- Goss, Monica;
- Nair, Rejani R;
- Patel, Vibhuti N;
- Snyder, Heather M;
- Tannous, Jonika D;
- Snitz, Beth E.;
- Ganguli, Mary;
- Seshadri, Sudha
Publication type:
Article
Preliminary neurocognitive finding from a multi‐site study investing long‐term neurological impact of COVID‐19 using ultra‐high field 7 Tesla MRI‐based neuroimaging.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079210
By:
- Tannous, Jonika D;
- Vahidy, Farhaan S;
- Patira, Riddhi;
- Luckey, Alison M.;
- Gonzales, Mitzi M.;
- Hosseini, Akram A.;
- Girard, Timothy D.;
- Ibrahim, Tamer;
- Jacobs, Heidi I.L.;
- Roman, Gustavo C;
- Masdeu, Joseph C.;
- Karmonik, Christof;
- Li, Karl;
- Garbarino, Valentina R.;
- Goss, Monica;
- Nair, Rejani R;
- Patel, Vibhuti N;
- Snyder, Heather M;
- de Erausquin, Gabriel A.;
- Ganguli, Mary
Publication type:
Article
Estimating a clinically normal individual's position along a preclinical Alzheimer's disease continuum using cognitive and amyloid trajectories.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078401
By:
- Townsend, Diana;
- Properzi, Michael J;
- Betthauser, Tobey J;
- Klinger, Hannah M;
- Boyle, Rory;
- Coughlan, Gillian T;
- Hanseeuw, Bernard J;
- Yang, Hyun‐Sik;
- Amariglio, Rebecca E.;
- Farrell, Michelle E.;
- Jacobs, Heidi I.L.;
- Shirzadi, Zahra;
- Yau, Wai‐Ying Wendy;
- Price, Julie C;
- Chhatwal, Jasmeer P.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Schultz, Aaron P.;
- Buckley, Rachel F.
Publication type:
Article
Lower LC activity during high arousal conditions is related to greater plasma P‐Tau217 concentration in older individuals.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079974
By:
- Prokopiou, Prokopis C.;
- Van Egroo, Maxime;
- Riphagen, Joost M.;
- Ashton, Nicholas J.;
- Janelidze, Shorena;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Blennow, Kaj;
- Hansson, Oskar;
- Zetterberg, Henrik;
- Jacobs, Heidi I.L.
Publication type:
Article
Braak‐stage II atrophy links lower locus coeruleus – medial temporal lobe connectivity to cognitive decline in preclinical AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079240
By:
- Schneider, Christoph;
- Prokopiou, Prokopis C.;
- Papp, Kathryn V.;
- Hsieh, Stephanie;
- Schultz, Aaron P.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Sex hormone binding globulin and total testosterone levels are associated with in vivo tau burden differentially between the sexes: findings from the Framingham Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080202
By:
- Buckley, Rachel F.;
- McGrath, Emer R;
- Scott, Matthew R;
- Coughlan, Gillian T;
- Boyle, Rory;
- Seto, Mabel;
- Ghosh, Saptaparni;
- Jacobs, Heidi I.L.;
- Satizabal, Claudia L.;
- Thibault, Emma G.;
- Vasan, Ramachandran S;
- Murabito, Joanne M;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Seshadri, Sudha;
- Jasuja, Ravi;
- Bhasin, Shalender;
- Beiser, Alexa S.
Publication type:
Article
Lower locus coeruleus integrity in older COVID‐19 survivors: initial findings from an international 7T MRI consortium.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080224
By:
- Jacobs, Heidi I.L.;
- Ibrahim, Tamer;
- Vahidy, Farhaan S;
- Girard, Timothy D.;
- Hosseini, Akram A.;
- Alkateeb, Salem;
- Bowtell, Richard;
- Penny, Gowland;
- Habes, Mohamad;
- Karmonik, Christof;
- Mougin, Olivier;
- Roman, Gustavo C;
- Masdeu, Joseph C.;
- Li, Karl;
- Garbarino, Valentina R.;
- Goss, Monica;
- Nair, Rejani R;
- Patel, Vibhuti N;
- Snyder, Heather M;
- Tannous, Jonika D
Publication type:
Article
Left Frontoparietal Connectivity Counteracts Locus Coeruleus‐Related Attentional Decline in Preclinical Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079733
By:
- Pahl, Jennifer;
- Prokopiou, Prokopis C.;
- Bueicheku, Elisenda;
- Schultz, Aaron P.;
- Papp, Kathryn V.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Association of focal epilepsy in Alzheimer's disease with tau, amyloid, and neurodegeneration.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079245
By:
- Lam, Alice D;
- Jacobs, Heidi I.L.;
- Thibault, Emma G.;
- Mayblyum, Danielle V.;
- Hsieh, Stephanie;
- Pellerin, Kyle R;
- Buss, Stephanie S.;
- Sarkis, Rani A;
- Johnson, Keith A.;
- Sperling, Reisa A.
Publication type:
Article
Examining the influence of changes in amyloid burden on both contemporaneous and subsequent cognitive decline: using a latent change score approach.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078893
By:
- Klinger, Hannah M;
- Healy, Brian;
- Hanseeuw, Bernard J;
- Jones, Rich;
- Townsend, Diana;
- Properzi, Michael J;
- Farrell, Michelle E.;
- Papp, Kathryn V.;
- Chhatwal, Jasmeer P.;
- Yang, Hyun‐Sik;
- Schultz, Aaron P.;
- Amariglio, Rebecca E.;
- Jacobs, Heidi I.L.;
- Price, Julie C;
- Johnson, Keith A.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Buckley, Rachel F.
Publication type:
Article
Locus coeruleus metabolic changes as a predictor of tau accumulation and cognitive decline.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073715
By:
- Koops, Elouise A.;
- Dutta, Joyita;
- Becker, Alex;
- Van Egroo, Maxime;
- Riphagen, Joost M.;
- Hanseeuw, Bernard J;
- Sperling, Reisa A.;
- Fakhri, Georges El;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Spatiotemporal Assessment of Locus Coeruleus Integrity Predicting Cortical Tau and Cognition.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079747
By:
- Bueichekú, Elisenda;
- Diez, Ibai Palacio;
- Kim, Chan‐Mi;
- Becker, Alex;
- Koops, Elouise A.;
- Kwong, Kenneth;
- Papp, Kathryn V.;
- Salat, David H;
- Bennett, David A. A;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Sepulcre, Jorge;
- Jacobs, Heidi I.L.
Publication type:
Article
Locus coeruleus integrity exhibits distinct anatomic vulnerabilities to regional tau and amyloid accumulation: parallel and intersecting mechanisms?
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072201
By:
- Jacobs, Heidi I.L.;
- Becker, Alex;
- Riphagen, Joost M.;
- Thibault, Emma G.;
- Farrell, Michelle E.;
- Properzi, Michael J;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Examining the influence of changes in amyloid burden on both contemporaneous and subsequent cognitive decline: using a latent change score approach.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081851
By:
- Klinger, Hannah M;
- Healy, Brian;
- Hanseeuw, Bernard J;
- Jones, Rich;
- Townsend, Diana;
- Properzi, Michael J;
- Farrell, Michelle E.;
- Papp, Kathryn V.;
- Chhatwal, Jasmeer P.;
- Yang, Hyun‐Sik;
- Schultz, Aaron P.;
- Amariglio, Rebecca E.;
- Jacobs, Heidi I.L.;
- Price, Julie C;
- Johnson, Keith A.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Buckley, Rachel F.
Publication type:
Article
Spatiotemporal Assessment of Locus Coeruleus Integrity Predicting Cortical Tau and Cognition.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079747
By:
- Bueichekú, Elisenda;
- Diez, Ibai Palacio;
- Kim, Chan‐Mi;
- Becker, Alex;
- Koops, Elouise A.;
- Kwong, Kenneth;
- Papp, Kathryn V.;
- Salat, David H;
- Bennett, David A. A;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Sepulcre, Jorge;
- Jacobs, Heidi I.L.
Publication type:
Article
Locus coeruleus integrity exhibits distinct anatomic vulnerabilities to regional tau and amyloid accumulation: parallel and intersecting mechanisms?
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072201
By:
- Jacobs, Heidi I.L.;
- Becker, Alex;
- Riphagen, Joost M.;
- Thibault, Emma G.;
- Farrell, Michelle E.;
- Properzi, Michael J;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
IC‐02‐04: REGIONAL ASYMMETRIES IN AMYLOID AND TAU GO TOGETHER: EVIDENCE FOR LOCAL INTERACTION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P4, doi. 10.1016/j.jalz.2018.06.2047
By:
- Jacobs, Heidi I.L.;
- Hanseeuw, Bernard J.;
- Vannini, Patrizia;
- Price, Julie C.;
- Dutta, Joyita;
- Becker, Alex;
- Pase, Matthew P.;
- Satizabal, Claudia L.;
- Beiser, Alexa S.;
- Demissie, Serkalem;
- Daniluk, Dan;
- Schafer, Colin;
- Peets, Bryanne;
- Killiany, Ronald;
- Sperling, Reisa A.;
- DeCarli, Charlie S.;
- Seshadri, Sudha;
- Johnson, Keith A.
Publication type:
Article
Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 1, p. 169, doi. 10.1002/alz.12656
By:
- Jacobs, Heidi I.L.;
- Becker, John Alex;
- Kwong, Kenneth;
- Munera, Diana;
- Ramirez‐Gomez, Liliana;
- Engels‐Domínguez, Nina;
- Sanchez, Justin S;
- Vila‐Castelar, Clara;
- Baena, Ana;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Lopera, Francisco;
- Quiroz, Yakeel T.
Publication type:
Article
Associations Between Mild Behavioral Impairment (MBI‐C) Affective Domains and Alzheimer's Disease Neuroimaging Biomarkers in Older Adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.068302
By:
- Mayblyum, Danielle V.;
- Quiroz, Yakeel T.;
- Langella, Stephanie;
- Udeogu, Onyinye J.;
- Jacobs, Heidi I.L.;
- Rubinstein, Zoe B.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Blacker, Deborah;
- Marshall, Gad A;
- Gatchel, Jennifer R
Publication type:
Article
Lower novelty‐related locus coeruleus function is associated with entorhinal tau‐mediated memory decline in older individuals.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.067706
By:
- Prokopiou, Prokopis C.;
- Engels, Nina;
- Schneider, Christoph;
- Schultz, Aaron P.;
- Sepulcre, Jorge;
- Riphagen, Joost M.;
- Koops, Elouise A.;
- Papp, Kathryn V.;
- Fakhri, Georges El;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Using 7T MRI to Evaluate COVID‐19 and Brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.066865
By:
- Hosseini, Akram A.;
- Bowtell, Richard;
- Mougin, Olivier;
- Penny, Gowland;
- Katshu, Mohammad Zia;
- Mukaetova‐Ladinska, Elizabeta;
- Ibrahim, Tamer;
- Girard, Timothy D.;
- Vahidy, Farhaan S.;
- Jacobs, Heidi I.L.;
- Snyder, Heather M.;
- de Erausquin, Gabriel A.;
- Seshadri, Sudha
Publication type:
Article
Vascular health is associated with locus coeruleus‐related entorhinal tau deposition.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.066731
By:
- Riphagen, Joost M.;
- Chhatwal, Jasmeer P.;
- Becker, Alex;
- Kwong, Kenneth;
- Engels, Nina;
- Yau, Wai‐Ying Wendy;
- Prokopiou, Prokopis C.;
- Schneider, Christoph;
- Koops, Elouise A.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Worse objective and subjective sleep‐wake metrics are associated with locus coeruleus hypopigmentation: a retrospective post‐mortem study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.066730
By:
- Van Egroo, Maxime;
- Jacobs, Heidi I.L.
Publication type:
Article
Longitudinal hippocampal atrophy is associated with cognitive decline independently of amyloid and tau in neocortex.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.069271
By:
- Hanseeuw, Bernard;
- Jacobs, Heidi I.L.;
- Schultz, Aaron P;
- Buckley, Rachel F.;
- Properzi, Michael J;
- Becker, Alex;
- Farrell, Michelle E.;
- Sanchez, Justin S;
- Papp, Kathryn V.;
- Yang, Hyun‐Sik;
- Chhatwal, Jasmeer P.;
- Price, Julie C;
- Fakhri, Georges El;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Optimizing early detection of beta‐amyloid accumulation with PET using spatial extent.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068029
By:
- Farrell, Michelle E.;
- Thibault, Emma G.;
- Becker, Alex;
- Price, Julie C;
- Schultz, Aaron P.;
- Properzi, Michael J;
- Buckley, Rachel F.;
- Jacobs, Heidi I.L.;
- Hanseeuw, Bernard;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Defining the ATN framework using longitudinal biomarker trajectories reveals an emerging amyloid accumulation group.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068001
By:
- Boyle, Rory Thomas;
- Coughlan, Gillian T;
- Properzi, Michael J;
- Archdeacon, Claire;
- Chou, Hsiang‐Chin Lori;
- Klinger, Hannah;
- Jacobs, Heidi I.L.;
- Papp, Kathryn V.;
- Amariglio, Rebecca E.;
- Farrell, Michelle E.;
- Donohue, Michael C.;
- Hohman, Timothy J.;
- Mormino, Elizabeth C.;
- Hanseeuw, Bernard J;
- Chhatwal, Jasmeer P.;
- Rentz, Dorene M.;
- Price, Julie C;
- Johnson, Keith A.;
- Schultz, Aaron P.;
- Sperling, Reisa A.
Publication type:
Article
Developing early vulnerable area aggregates for PET detection of beta‐amyloid based on young and middle‐aged adults from the Framingham Heart Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.067870
By:
- Thibault, Emma G.;
- Farrell, Michelle E.;
- Beiser, Alexa S;
- Becker, Alex;
- Satizabal, Claudia L;
- Jacobs, Heidi I.L.;
- DeCarli, Charles S.;
- Hanseeuw, Bernard;
- Killiany, Ronald J;
- Sperling, Reisa A.;
- Seshadri, Sudha;
- Johnson, Keith A.
Publication type:
Article
Plasma ptau231 predicts locus coeruleus integrity earlier in life than other Alzheimer's disease plasma markers: a 7T MRI study across the adult lifespan.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.065878
By:
- Jacobs, Heidi I.L.;
- Riphagen, Joost M.;
- Ashton, Nicholas J.;
- Janelidze, Shorena;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Yang, Hyun‐Sik;
- Blennow, Kaj;
- Hansson, Oskar;
- Zetterberg, Henrik;
- Van Egroo, Maxime
Publication type:
Article
Cognitive‐behavioral associations of amygdala subregional tau pathology in cognitively unimpaired Presenilin‐1 E280A mutation carriers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.067650
By:
- Langella, Stephanie;
- Sanchez, Justin S;
- Martinez, Jairo E.;
- Rubinstein, Zoe B.;
- Baena, Ana Y.;
- Vila‐Castelar, Clara;
- Ramirez‐Gomez, Liliana A.;
- Aduen, Paula;
- Jacobs, Heidi I.L.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Lopera, Francisco;
- Gatchel, Jennifer R;
- Quiroz, Yakeel T.
Publication type:
Article
Lower in‐vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer's pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.067421
By:
- Engels, Nina;
- Hsieh, Stephanie;
- Schneider, Christoph;
- Prokopiou, Prokopis C.;
- Schultz, Aaron P.;
- Riphagen, Joost M.;
- Koops, Elouise A.;
- Hanseeuw, Bernard;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Characterisation of pupillary responses to alternating blue and orange light exposures in a fMRI protocol.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.066518
By:
- Beckers, Elise;
- Campbell, Islay;
- Paparella, Ilenia;
- Sharifpour, Roya;
- Ekaterina, Koshmanova;
- Berger, Alexandre;
- Sherif, Siya;
- Jacobs, Heidi I.L.;
- Gilles, Vandewalle
Publication type:
Article
Relationships between locus coeruleus structural integrity and nocturnal awakenings in the context of AD biomarkers: A 7T MRI study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.055326
By:
- Van Egroo, Maxime;
- van Hooren, Roy W.E.;
- Jacobs, Heidi I.L.
Publication type:
Article
Amygdala tau pathology in preclinical autosomal dominant Alzheimer’s disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057853
By:
- Sanchez, Justin S.;
- Martinez, Jairo E.;
- Rubinstein, Zoe B.;
- Baena, Ana Y.;
- Vila‐Castelar, Clara;
- Fox‐Fuller, Joshua T.;
- Gatchel, Jennifer R.;
- Ramirez‐Gomez, Liliana A.;
- Aduen, Paula;
- Guzman‐Velez, Edmarie;
- Pluim, Celina F.;
- Jacobs, Heidi I.L.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Lopera, Francisco;
- Quiroz, Yakeel T.
Publication type:
Article
Regional beta‐amyloid and tau deposition: Results from the Framingham Heart Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056508
By:
- Thibault, Emma G.;
- Farrell, Michelle E.;
- Beiser, Alexa S.;
- Sanchez, Justin S.;
- Satizabal, Claudia L.;
- Mayblyum, Danielle V.;
- O’Donnell, Adrienne;
- Rubinstein, Zoe B.;
- Jacobs, Heidi I.L.;
- DeCarli, Charles S.;
- Hanseeuw, Bernard;
- Killiany, Ronald J.;
- Sperling, Reisa A.;
- Seshadri, Sudha;
- Johnson, Keith A.
Publication type:
Article
Locus coeruleus integrity as a proxy of initial tau burden: in vivo versus ex vivo observations.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056391
By:
- Jacobs, Heidi I.L.;
- Becker, Alex;
- Kwong, Kenneth;
- Engels, Nina;
- Prokopiou, Prokopis C.;
- Papp, Kate V.;
- Properzi, Michael J;
- Hampton, Olivia L.;
- Sanchez, Justin S.;
- Rentz, Dorene M.;
- Fakhri, Georges El;
- Normandin, Marc D.;
- Bennett, David A.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Sequential early cognitive changes sensitive to rising beta‐amyloid and tau pathology in preclinical AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056315
By:
- Farrell, Michelle E.;
- Papp, Kate V.;
- Buckley, Rachel F.;
- Jacobs, Heidi I.L.;
- Schultz, Aaron P;
- Properzi, Michael J;
- Vannini, Patrizia;
- Hanseeuw, Bernard;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.
Publication type:
Article
Longitudinal associations between amyloid and tau‐PET: Impact for prevention trials.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056208
By:
- Hanseeuw, Bernard;
- Jacobs, Heidi I.L.;
- Becker, Alex;
- Buckley, Rachel F.;
- Properzi, Michael J.;
- Farrell, Michelle E.;
- Schultz, Aaron P.;
- Sanchez, Justin S.;
- Chhatwal, Jasmeer P.;
- Price, Julie C.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Self‐reported history of estrogen hormone therapy differentiates rates of amyloid accumulation (PiB‐PET) relative to males: Findings from the Harvard Aging Brain Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056069
By:
- Rubinstein, Zoe B.;
- Buckley, Rachel F.;
- Scott, Matthew R.;
- Manning, Lyssa K.;
- Mayblyum, Danielle V.;
- Thibault, Emma G.;
- Jacobs, Heidi I.L.;
- Farrell, Michelle E.;
- Properzi, Michael J.;
- Rabin, Jennifer S.;
- Chhatwal, Jasmeer P.;
- Lois, Cristina;
- Rentz, Dorene;
- Price, Julie C.;
- Schultz, Aaron P.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Brainstem volume is negatively associated with amyloid deposition in the Framingham Heart Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.055851
By:
- Jacobs, Heidi I.L.;
- O’Donnell, Adrienne;
- Satizabal, Claudia L.;
- Hanseeuw, Bernard;
- Thibault, Emma G.;
- Koijs, Daniel;
- Sanchez, Justin S.;
- Buckley, Rachel F.;
- Yang, Qiong;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Beiser, Alexa S.;
- Seshadri, Sudha
Publication type:
Article
Menopause moderates sex differences in tau PET signal: Findings from the Framingham Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054966
By:
- Buckley, Rachel F.;
- O'Donnell, Adrienne;
- McGrath, Emer R.;
- Jacobs, Heidi I.L.;
- Satizabal, Claudia L.;
- Ghosh, Saptaparni;
- Rubinstein, Zoe B.;
- Murabito, Joanne M.;
- Sperling, Reisa A.;
- Beiser, Alexa S.;
- Seshadri, Sudha
Publication type:
Article

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