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- Title
Thermodynamic Study on Antibacterial Effect of Different Extracts from Radix Isatis.
- Authors
Zhao Yan-Ling; Qu Fen; Xiao Xiao-He; Liao Qing-Wen; Wang Jia-bo; Ma Yong-Gang; Sun Yu-Qi
- Abstract
Objective: To study and analyze the antibacterial effects of different extracts from Radix Isatis. Methods: Staphylococcus aureus was used as the studied object in the experiment. Antibacterial effects of extracts from Radix Isatis were observed by thermocalrimetry on Staphylococcus aureus, together with common pharmacological experiments. Results: The total extract, ethyl acetate (EtOAc) extract, n-butylalcohol (nBuOH) extract, chloroform (CHCl3) extract and petroleum (P.E.) extract had antiviral effects to some extent while the residue after extracting had no antibacterial activity. The potency of antiviral activity among them was as follows: nBuOH extract > EtOAc extract > CHCl3 extract > total extract > P.E. extract. Conclusion: The antibacteriall effects of Radix Isatis were not limited to any active portion, showing that Radix Isatis exerts its antibacterial effects by cooperation of different active fractions in varied ways.
- Subjects
ANTIBACTERIAL agents; EXTRACTS; STAPHYLOCOCCUS aureus; PHARMACOLOGY; ANTIVIRAL agents
- Publication
Chinese Journal of Integrative Medicine, 2006, Vol 12, Issue 1, p42
- ISSN
1672-0415
- Publication type
Article
- DOI
10.1007/BF02857429