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- Title
Lipid Droplet Metabolism Across Eukaryotes: Evidence from Yeast to Humans.
- Authors
Huang, Jie; Chen, Xiaojia; Zhang, Feilong; Lin, Margarita; Lin, Guorong; Zhang, Zhizhen
- Abstract
The lipid droplet (LD) is a highly dynamic organelle that maintains cellular lipid homeostasis in addition to storing energy sources. Current research suggests LDs are responsible for the transportation, storage and lipolysis-driven mobilization of lipids within cells. Here, we review the landscape of evidence for LD involvement in regulating lipid homeostasis. LD interactions with other organelles, particularly the endoplasmic reticulum, mitochondria, lysosomes (or vacuoles in yeast), and peroxisomes, highlight their importance for lipid transfer and metabolism.
- Subjects
LYSOSOMES; LIPID metabolism; PERILIPIN; ENDOPLASMIC reticulum; YEAST
- Publication
Journal of Evolutionary Biochemistry & Physiology, 2020, Vol 56, Issue 5, p396
- ISSN
0022-0930
- Publication type
Article
- DOI
10.1134/S0022093020050026