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- Title
Migraine with aura: A predictor of patent foramen ovale in children and adolescents.
- Authors
Choi, Deok Young; Shin, Dong Hoon; Cho, Kang Ho; Lee, Sang Pyo; Park, Sanghui
- Abstract
Background: The prevalence of patent foramen ovale (PFO) is higher among adult migraine patients. The purpose of thisstudy was to determine the frequency of PFO in children and adolescent migraine patients.Methods and results: A total of 32 patients with migraine (divided into two subgroups, the migraine with aura subgroupand the migraine without aura subgroup) and 31 normal control subjects were enrolled in this study. All of the participantsunderwent transthoracic echocardiography with an agitated saline test. We compared the prevalence of PFO andthe severity of right-to-left shunt (RLS) in each group. No statistical difference in age and sex ratio was observed in eithergroup. The prevalence of PFO was higher in the migraine group than in the control group, but without statisticalsignificance (46.9% vs. 25.8%, p=0.084). The prevalence of PFO was significantly higher in the migraine with aurasubgroup than in the migraine without aura subgroup (p=0.031) and the normal control group (p=0.0074).Migraine with aura was the only significant factor showing an association with PFO (<0.01). RLS size did not have aninfluence on migraine.Conclusions: Considering the significantly high prevalence of PFO in pediatric migraine with aura patients, migraine withaura is a clear predictor of PFO among children and adolescents.
- Subjects
MIGRAINE aura; JUVENILE diseases; DISEASES in teenagers; ECHOCARDIOGRAPHY; DISEASE prevalence
- Publication
Cephalalgia, 2013, Vol 33, Issue 7, p463
- ISSN
0333-1024
- Publication type
Article
- DOI
10.1177/0333102413477740