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Recent Advances in Translational Pharmacokinetics and Pharmacodynamics Prediction of Therapeutic Antibodies Using Modeling and Simulation.
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- Pharmaceuticals (14248247), 2022, v. 15, n. 5, p. 508, doi. 10.3390/ph15050508
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- Article
Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment.
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- Pharmaceutical Research, 2021, v. 38, n. 6, p. 1031, doi. 10.1007/s11095-021-03054-4
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- Article
Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization.
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- Nature Biotechnology, 2010, v. 28, n. 11, p. 1203, doi. 10.1038/nbt.1691
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- Article
A Novel Total Drug Assay for Quantification of Anti-C5 Therapeutic Monoclonal Antibody in the Presence of Abundant Target.
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- AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00539-9
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- Article
Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity <i>In Vivo</i>
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063236
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- Article
Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity.
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- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057479
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- Article
Regulation of <it>CAPRICE</it> Transcription by MYB Proteins for Root Epidermis Differentiation in <it>Arabidopsis</it>.
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- Plant & Cell Physiology, 2005, v. 46, n. 6, p. 817, doi. 10.1093/pcp/pci096
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- Article
Quantitative prediction of CYP3A‐mediated drug–drug interactions by correctly estimating fraction metabolized using human liver chimeric mice.
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- British Journal of Pharmacology, 2024, v. 181, n. 7, p. 1091, doi. 10.1111/bph.16270
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- Article
Quantitative prediction of P‐glycoprotein‐mediated drug–drug interactions and intestinal absorption using humanized mice.
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- British Journal of Pharmacology, 2021, v. 178, n. 21, p. 4335, doi. 10.1111/bph.15612
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- Article
Estimation of Clearance and Bioavailability of Therapeutic Monoclonal Antibodies from Only Subcutaneous Injection Data in Humans Based on Comprehensive Analysis of Clinical Data.
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- Clinical Pharmacokinetics, 2021, v. 60, n. 10, p. 1325, doi. 10.1007/s40262-021-01023-z
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- Article
Simple Approach to Accurately Predict Pharmacokinetics of Therapeutic Monoclonal Antibodies after Subcutaneous Injection in Humans.
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- Clinical Pharmacokinetics, 2021, v. 60, n. 1, p. 111, doi. 10.1007/s40262-020-00917-8
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- Article
Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody.
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- PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0209509
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- Article
Translational Approach for Predicting Human Pharmacokinetics of Engineered Therapeutic Monoclonal Antibodies with Increased FcRn-Binding Mutations.
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- BioDrugs, 2023, v. 37, n. 1, p. 99, doi. 10.1007/s40259-022-00566-2
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- Article
Prediction of Nonlinear Intestinal Absorption of CYP3A4 and P-Glycoprotein Substrates from their In Vitro Km Values.
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- Pharmaceutical Research, 2012, v. 29, n. 3, p. 651, doi. 10.1007/s11095-011-0579-2
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- Article
Model Analysis of the Concentration-Dependent Permeability of P-gp Substrates.
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- Pharmaceutical Research, 2010, v. 27, n. 3, p. 442, doi. 10.1007/s11095-009-0026-9
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- Article