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- Title
Predictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chinese.
- Authors
Lee, Jacky W. Y.; Liu, Catherine C. L.; Chan, Jonathan C. H.; Wong, Raymond L. M.; Wong, Ian Y. H.; Lai, Jimmy S. M.
- Abstract
Purpose: To determine the predictors of success for adjuvant selective laser trabeculoplasty (SLT) in Chinese primary open angle glaucoma (POAG) patients. Methods: This prospective study recruited Chinese subjects with unilateral or bilateral POAG currently taking medication to reduce intraocular pressure (IOP). All subjects received a single session of 360° SLT treatment and continued their medications for 1 month. SLT success was defined as IOP reduction ≥20% at 1 month. The following covariates were analyzed in both groups via univariate and multivariate analyses: age, sex, lens status, initial IOPs, post-SLT IOPs, number and type of medications, SLT shots and energy, and pre-SLT investigations. Results: In 51 eyes of 33 POAG subjects, the success rate of SLT was 47.1%. Certain groups of patients were associated with greater success using univariate analysis. These groups included the following: older age (coefficient =0.1; OR: 1.1; P=0.0003), a higher pre-SLT IOP (coefficient =0.3; OR: 1.3; P=0.0005), using four types of antiglaucoma medication (coefficient =2.1; OR: 8.4; P=0.005), a greater degree of spherical equivalent (coefficient =2.1; OR: 8.4; P=0.005), and the use of a topical carbonic anhydrase inhibitor (coefficient =1.7; OR: 6.0; P=0.003). None of the covariates were significant using multivariate analysis. Conclusion: Older age, a higher pretreatment IOP, using multiple antiglaucoma medications especially topical carbonic anhydrase inhibitor, and higher refractive errors were associated with greater SLT success.
- Subjects
GLAUCOMA surgery; EYE diseases; INTRAOCULAR pressure; UNIVARIATE analysis; REFRACTIVE errors
- Publication
Clinical Ophthalmology, 2014, Vol 8, p1787
- ISSN
1177-5467
- Publication type
Article
- DOI
10.2147/OPTH.S69166