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- Title
MANUALLY ASSISTED BODY-WEIGHT SUPPORTED LOCOMOTOR TRAINING DOES NOT RE-ESTABLISH WALKING IN NON-WALKING SUBJECTS WITH CHRONIC INCOMPLETE SPINAL CORD INJURY: A RANDOMIZED CLINICAL TRIAL.
- Authors
PIIRA, Anu; LANNEM, Anne M.; SØRENSEN, Marit; GLOTT, Thomas; KNUTSEN, Raymond; JØRGENSEN, Lone; GJESDAL, Knut; HJELTNES, Nils; KNUTSEN, Synnøve F.
- Abstract
Objective: To assess the effects of manually assisted body-weight supported locomotor training in subjects with chronic incomplete spinal cord injury. Design: Randomized controlled clinical trial. Subjects: Twenty subjects with American Spinal Injury Association Impairment Scale grades C or D and > 2 years post-injury. Methods: Random allocation to 60 days of bodyweight supported locomotor training, or usual care, which might include over-ground walking. Walking function, lower extremity muscle strength and balance were blindly evaluated pre-/post-intervention. Results: A small, non-significant improvement in walking function was observed (0.1 m/s (95% confidence interval (95% CI) -0.2, 0.4)), but subjects without baseline gait function, did not re-establish walking. The effect on lower extremity muscle strength was 2.7 points (95% CI -1.4, 6.8). No difference was observed in balance measures. Conclusion: Subjects with chronic incomplete spinal cord injury without baseline walking function were unable to re-establish gait with manually assisted body-weight supported locomotor training. A modest, non-significant, improvement was found in strength and walking speed. However, due to study recruitment problems, an effect size that was smaller than anticipated, and large functional heterogeneity among study subjects, the effect of late-onset body-weight supported locomotor training is not clear. Future studies should include larger numbers of subjects with less functional loss and greater functional homogeneity. Intensive training should probably start earlier post-injury.
- Subjects
NORWAY; BODY weight; CHI-squared test; CONFIDENCE intervals; POSTURAL balance; FISHER exact test; GAIT disorder treatment; MUSCLE strength; REGRESSION analysis; RESEARCH funding; STATISTICAL sampling; SPINAL cord injuries; STATISTICS; T-test (Statistics); WALKING; DATA analysis; AEROBIC capacity; RANDOMIZED controlled trials; BLIND experiment; DATA analysis software; DESCRIPTIVE statistics; WALKING speed; MANN Whitney U Test; BODY-weight-supported treadmill training
- Publication
Journal of Rehabilitation Medicine (Stiftelsen Rehabiliteringsinformation), 2019, Vol 51, Issue 2, p113
- ISSN
1650-1977
- Publication type
Article
- DOI
10.2340/16501977-2508