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Structural basis of lipid biosynthesis regulation in Gram-positive bacteria.
Published in:
EMBO Journal, 2006, v. 25, n. 17, p. 4074, doi. 10.1038/sj.emboj.7601284
By:
- Schujman, Gustavo E.;
- Guerin, Marcelo;
- Buschiazzo, Alejandro;
- Schaeffer, Francis;
- Llarrull, Leticia I.;
- Reh, Georgina;
- Vila, Alejandro J.;
- Alzari, Pedro M.;
- de Mendoza, Diego
Publication type:
Article
Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation.
Published in:
EMBO Journal, 2004, v. 23, n. 16, p. 3196, doi. 10.1038/sj.emboj.7600324
By:
- Buschiazzo, Alejandro;
- Ugalde, Juan E.;
- Guerin, Marcelo E.;
- Shepard, William;
- Ugalde, Rodolfo A.;
- Alzari, Pedro M.
Publication type:
Article
Structural basis of sialyltransferase activity in trypanosomal sialidases.
Published in:
EMBO Journal, 2000, v. 19, n. 1, p. 16, doi. 10.1093/emboj/19.1.16
By:
- Buschiazzo, Alejandro;
- Tavares, Gisele A.;
- Campetella, Oscar;
- Spinelli, Silvia;
- Cremona, Marfa L.;
- París, Gastón;
- Amaya, Maria Fernanda;
- Frasch, Alberto C. C.;
- Alzari, Pedro M.
Publication type:
Article
Crystallization of FcpA from Leptospira, a novel flagellar protein that is essential for pathogenesis.
Published in:
Acta Crystallographica: Section F, Structural Biology Communications, 2017, v. 73, n. 3, p. 123, doi. 10.1107/S2053230X17002096
By:
- San Martin, Fabiana;
- Mechaly, Ariel E.;
- Larrieux, Nicole;
- Wunder, Elsio A.;
- Ko, Albert I.;
- Picardeau, Mathieu;
- Trajtenberg, Felipe;
- Buschiazzo, Alejandro
Publication type:
Article
Regulation of signaling directionality revealed by 3D snapshots of a kinase: regulator complex in action.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.21422
By:
- Trajtenberg, Felipe;
- Imelio, Juan A.;
- Machado, Matías R.;
- Larrieux, Nicole;
- Marti, Marcelo A.;
- Obal, Gonzalo;
- Mechaly, Ariel E.;
- Buschiazzo, Alejandro
Publication type:
Article
What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira.
Published in:
PLoS Neglected Tropical Diseases, 2016, v. 10, n. 2, p. 1, doi. 10.1371/journal.pntd.0004403
By:
- Fouts, Derrick E.;
- Matthias, Michael A.;
- Adhikarla, Haritha;
- Adler, Ben;
- Amorim-Santos, Luciane;
- Berg, Douglas E.;
- Bulach, Dieter;
- Buschiazzo, Alejandro;
- Chang, Yung-Fu;
- Galloway, Renee L.;
- Haake, David A.;
- Haft, Daniel H.;
- Hartskeerl, Rudy;
- Ko, Albert I.;
- Levett, Paul N.;
- Matsunaga, James;
- Mechaly, Ariel E.;
- Monk, Jonathan M.;
- Nascimento, Ana L. T.;
- Nelson, Karen E.
Publication type:
Article
Active nuclear import and cytoplasmic retention of activation-induced deaminase.
Published in:
Nature Structural & Molecular Biology, 2009, v. 16, n. 5, p. 517, doi. 10.1038/nsmb.1598
By:
- Patenaude, Anne-Marie;
- Orthwein, Alexandre;
- Yi Hu;
- Campo, Vanina A.;
- Kavli, Bodil;
- Buschiazzo, Alejandro;
- Di Noia, Javier M.
Publication type:
Article
Crystal structure of Mycobacterium tuberculosis LppA, a lipoprotein confined to pathogenic mycobacteria.
Published in:
Proteins, 2010, v. 78, n. 3, p. 769, doi. 10.1002/prot.22603
By:
- Graña, Martin;
- Bellinzoni, Marco;
- Bellalou, Jacques;
- Haouz, Ahmed;
- Miras, Isabelle;
- Buschiazzo, Alejandro;
- Winter, Nathalie;
- Alzari, Pedro M.
Publication type:
Article
Probing molecular function oftrypanosomal sialidases: single point mutations can change substratespecificity and increase hydrolytic activity.
Published in:
Glycobiology, 2001, v. 11, n. 4, p. 305, doi. 10.1093/glycob/11.4.305
By:
- Paris, Gaston;
- Cremona, Maria Laura;
- Amaya, Maria Fernanda;
- Buschiazzo, Alejandro;
- Giambiagi, Susana;
- Frasch, Alberto C.C.;
- Alzari, Pedro M.
Publication type:
Article
Trypanosoma rangeli sialidase: cloning, expression and similarity to T.cruzi trans-sialidase.
Published in:
Glycobiology, 1997, v. 7, n. 12, p. 1167, doi. 10.1093/glycob/7.8.1167
By:
- Buschiazzo, Alejandro;
- Campetella, Oscar;
- Frasch, Alberto C. C.
Publication type:
Article
Trypanosoma rangeli sialidase: cloning, expression and similarity to T.cruzi trans-sialidase.
Published in:
Glycobiology, 1997, v. 7, n. 8, p. 1167, doi. 10.1093/glycob/7.8.1167
By:
- Buschiazzo, Alejandro;
- Campetella, Oscar;
- Frasch, Alberto C. C.
Publication type:
Article
Role of the major determinant of polar flagellation FlhG in the endoflagella‐containing spirochete Leptospira.
Published in:
Molecular Microbiology, 2021, v. 116, n. 5, p. 1392, doi. 10.1111/mmi.14831
By:
- Fule, Lenka;
- Halifa, Ruben;
- Fontana, Celia;
- Sismeiro, Odile;
- Legendre, Rachel;
- Varet, Hugo;
- Coppée, Jean‐Yves;
- Murray, Gerald L.;
- Adler, Ben;
- Hendrixson, David R.;
- Buschiazzo, Alejandro;
- Guo, Shuaiqi;
- Liu, Jun;
- Picardeau, Mathieu
Publication type:
Article
A novel flagellar sheath protein, FcpA, determines filament coiling, translational motility and virulence for the Leptospira spirochete.
Published in:
Molecular Microbiology, 2016, v. 101, n. 3, p. 457, doi. 10.1111/mmi.13403
By:
- Wunder, Elsio A.;
- Figueira, Cláudio P.;
- Benaroudj, Nadia;
- Hu, Bo;
- Tong, Brian A.;
- Trajtenberg, Felipe;
- Liu, Jun;
- Reis, Mitermayer G.;
- Charon, Nyles W.;
- Buschiazzo, Alejandro;
- Picardeau, Mathieu;
- Ko, Albert I.
Publication type:
Article
A coiled coil switch mediates cold sensing by the thermosensory protein DesK.
Published in:
Molecular Microbiology, 2015, v. 98, n. 2, p. 258, doi. 10.1111/mmi.13118
By:
- Saita, Emilio;
- Abriata, Luciano A.;
- Tsai, Yi Ting;
- Trajtenberg, Felipe;
- Lemmin, Thomas;
- Buschiazzo, Alejandro;
- Dal Peraro, Matteo;
- Mendoza, Diego;
- Albanesi, Daniela
Publication type:
Article
Hem R is an Omp R/ Pho B-like response regulator from L eptospira, which simultaneously effects transcriptional activation and repression of key haem metabolism genes.
Published in:
Molecular Microbiology, 2014, v. 94, n. 2, p. 340, doi. 10.1111/mmi.12763
By:
- Morero, Natalia R.;
- Botti, Horacio;
- Nitta, Kazuhiro R.;
- Carrión, Federico;
- Obal, Gonzalo;
- Picardeau, Mathieu;
- Buschiazzo, Alejandro
Publication type:
Article
Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis.
Published in:
PLoS Neglected Tropical Diseases, 2018, v. 12, n. 9, p. 1, doi. 10.1371/journal.pntd.0006694
By:
- null, null;
- Nieves, Cecilia;
- Zarantonelli, Leticia;
- Buschiazzo, Alejandro;
- Hamond, Camila;
- Suanes, Alejandra;
- Salaberry, Ximena;
- Easton, Cristina;
- Mortola, Alberto;
- Meny, Paulina;
- Ashfield, Natalia;
- Menéndez, Clara;
- Quintero, Jair;
- Ríos, Cristina;
- Varela, Gustavo;
- Schelotto, Felipe;
- Buroni, Florencia;
- Rodríguez, Víctor;
- Rivero, Rodolfo;
- Briano, Carolina
Publication type:
Article
Structural insights into bacterial resistance to cerulenin.
Published in:
FEBS Journal, 2014, v. 281, n. 10, p. 2324, doi. 10.1111/febs.12785
By:
- Trajtenberg, Felipe;
- Altabe, Silvia;
- Larrieux, Nicole;
- Ficarra, Florencia;
- Mendoza, Diego;
- Buschiazzo, Alejandro;
- Schujman, Gustavo E.
Publication type:
Article
Structural features of sensory two component systems: a synthetic biology perspective.
Published in:
Biochemical Journal, 2023, v. 480, n. 2, p. 127, doi. 10.1042/BCJ20210798
By:
- Nieves, Marcos;
- Buschiazzo, Alejandro;
- Trajtenberg, Felipe
Publication type:
Article
FcpB Is a Surface Filament Protein of the Endoflagellum Required for the Motility of the Spirochete <italic>Leptospira</italic>.
Published in:
Frontiers in Cellular & Infection Microbiology, 2018, v. 8, p. N.PAG, doi. 10.3389/fcimb.2018.00130
By:
- Wunder, Elsio A.;
- Slamti, Leyla;
- Suwondo, David N.;
- Gibson, Kimberley H.;
- Shang, Zhiguo;
- Sindelar, Charles V.;
- Trajtenberg, Felipe;
- Buschiazzo, Alejandro;
- Ko, Albert I.;
- Picardeau, Mathieu
Publication type:
Article
Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira.
Published in:
Frontiers in Cellular & Infection Microbiology, 2018, v. 8, p. 1, doi. 10.3389/fcimb.2018.00045
By:
- Adhikarla, Haritha;
- Wunder, Elsio A.;
- Mechaly, Ariel E.;
- Mehta, Sameet;
- Wang, Zheng;
- Santos, Luciane;
- Bisht, Vimla;
- Diggle, Peter;
- Murray, Gerald;
- Adler, Ben;
- Lopez, Francesc;
- Townsend, Jeffrey P.;
- Groisman, Eduardo;
- Picardeau, Mathieu;
- Buschiazzo, Alejandro;
- Ko, Albert I.
Publication type:
Article
Data publication with the structural biology data grid supports live analysis.
Published in:
Nature Communications, 2016, v. 7, n. 3, p. 10882, doi. 10.1038/ncomms10882
By:
- Meyer, Peter A.;
- Socias, Stephanie;
- Key, Jason;
- Ransey, Elizabeth;
- Tjon, Emily C.;
- Buschiazzo, Alejandro;
- Lei, Ming;
- Botka, Chris;
- Withrow, James;
- Neau, David;
- Rajashankar, Kanagalaghatta;
- Anderson, Karen S.;
- Baxter, Richard H.;
- Blacklow, Stephen C.;
- Boggon, Titus J.;
- Bonvin, Alexandre M. J. J.;
- Borek, Dominika;
- Brett, Tom J.;
- Caflisch, Amedeo;
- Chang, Chung-I
Publication type:
Article
Signal-sensing triggers the shutdown of HemKR, regulating heme and iron metabolism in the spirochete Leptospira biflexa.
Published in:
PLoS ONE, 2024, v. 19, n. 9, p. 1, doi. 10.1371/journal.pone.0311040
By:
- Imelio, Juan Andrés;
- Trajtenberg, Felipe;
- Mondino, Sonia;
- Zarantonelli, Leticia;
- Vitrenko, Iakov;
- Lemée, Laure;
- Cokelaer, Thomas;
- Picardeau, Mathieu;
- Buschiazzo, Alejandro
Publication type:
Article
Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus aureus.
Published in:
PLoS Pathogens, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.ppat.1003108
By:
- Albanesi, Daniela;
- Reh, Georgina;
- Guerin, Marcelo E.;
- Schaeffer, Francis;
- Debarbouille, Michel;
- Buschiazzo, Alejandro;
- Schujman, Gustavo E.;
- De Mendoza, Diego;
- Alzari, Pedro M.
Publication type:
Article
Trypanosoma cruzi trans-Sialidase in Complex with a Neutralizing Antibody: Structure/Function Studies towards the Rational Design of Inhibitors.
Published in:
PLoS Pathogens, 2012, v. 8, n. 1, p. 1, doi. 10.1371/journal.ppat.1002474
By:
- Buschiazzo, Alejandro;
- Muiá, Romina;
- Larrieux, Nicole;
- Pitcovsky, Tamara;
- Mucci, Juan;
- Campetella, Oscar
Publication type:
Article
SIMBAD: a sequence‐independent molecular‐replacement pipeline.
Published in:
Acta Crystallographica: Section D, Structural Biology, 2018, v. 74, n. 7, p. 595, doi. 10.1107/S2059798318005752
By:
- Simpkin, Adam J.;
- Simkovic, Felix;
- Thomas, Jens M. H.;
- Savko, Martin;
- Lebedev, Andrey;
- Uski, Ville;
- Ballard, Charles;
- Wojdyr, Marcin;
- Wu, Rui;
- Sanishvili, Ruslan;
- Xu, Yibin;
- Lisa, María-Natalia;
- Buschiazzo, Alejandro;
- Shepard, William;
- Rigden, Daniel J.;
- Keegan, Ronan M.
Publication type:
Article
Listeria innocua isolated from diseased ruminants harbour minor virulence genes of L. monocytogenes.
Published in:
Veterinary Medicine & Science, 2022, v. 8, n. 2, p. 735, doi. 10.1002/vms3.710
By:
- Matto, Carolina;
- D'Alessandro, Bruno;
- Mota, María Inés;
- Braga, Valeria;
- Buschiazzo, Alejandro;
- Gianneechini, Edgardo;
- Varela, Gustavo;
- Rivero, Rodolfo
Publication type:
Article
An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis.
Published in:
Science Signaling, 2023, v. 16, n. 769, p. 1, doi. 10.1126/scisignal.abo7588
By:
- Lima, Sofía;
- Blanco, Juan;
- Olivieri, Federico;
- Imelio, Juan A.;
- Nieves, Marcos;
- Carrión, Federico;
- Alvarez, Beatriz;
- Buschiazzo, Alejandro;
- Marti, Marcelo A.;
- Trajtenberg, Felipe
Publication type:
Article
Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes.
Published in:
Archives of Virology, 2010, v. 155, n. 4, p. 481, doi. 10.1007/s00705-010-0606-3
By:
- Moratorio, Gonzalo;
- Obal, Gonzalo;
- Dubra, Ana;
- Correa, Agustín;
- Bianchi, Sergio;
- Buschiazzo, Alejandro;
- Cristina, Juan;
- Pritsch, Otto
Publication type:
Article
The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria.
Published in:
Protein Science: A Publication of the Protein Society, 2007, v. 16, n. 9, p. 1896, doi. 10.1110/ps.072982707
By:
- Graña, Martin;
- Haouz, Ahmed;
- Buschiazzo, Alejandro;
- Miras, Isabelle;
- Wehenkel, Annemarie;
- Bondet, Vincent;
- Shepard, William;
- Schaeffer, Francis;
- Cole, Stewart T.;
- Alzari, Pedro M.
Publication type:
Article
Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17504-x
By:
- Lara, Julia;
- Diacovich, Lautaro;
- Trajtenberg, Felipe;
- Larrieux, Nicole;
- Malchiodi, Emilio L.;
- Fernández, Marisa M.;
- Gago, Gabriela;
- Gramajo, Hugo;
- Buschiazzo, Alejandro
Publication type:
Article
A New Generation of Specific Trypanosoma cruzi trans-Sialidase Inhibitors.
Published in:
Angewandte Chemie International Edition, 2008, v. 47, n. 14, p. 2700, doi. 10.1002/anie.200705435
By:
- Buchini, Sabrina;
- Buschiazzo, Alejandro;
- Withers, Stephen G.
Publication type:
Article

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