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- Title
The effect of alteration in the sulcular environment upon the movement of <sup>14</sup>C-diphenylhydantoin through rabbit sulcular tissues.
- Authors
Steinberg, Arnold D.; Steinberg, June; Allen, Pamela; Jeffay, Henry
- Abstract
The kinetics of uptake and transport into blood after two hours of incubation, of diphenyl-hydantoin (DPH) appears to be of the saturation type, (i.e. linear with the amount of DPH available for transport), but at higher DPH concentration the transport rate is markedly decreased. insights into the properties of the transport system are gained by studying the effects of substances believed to alter cell membrane properties. The addition of 0.03 M potassium fluoride or 0.03 M sodium cyanide in gingival sulcus significantly alters the uptake of 14C-DPH by serum. These findings and use of this methodology have important implications in the study of sulcular tissue physiology and pathology.
- Subjects
TISSUES; SERUM; CELL membranes; BIOLOGICAL membranes; HEALTH care rationing; POTASSIUM
- Publication
Journal of Periodontal Research, 1976, Vol 11, Issue 1, p47
- ISSN
0022-3484
- Publication type
Article
- DOI
10.1111/j.1600-0765.1976.tb00049.x