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- Title
Homing Receptor Expression on Cord Blood T Lymphocytes and the Development of Atopic Eczema in Infants.
- Authors
Kohno, Yoichi; Shimojo, Naoki; Kojima, Hiroyuki; Katsuki, Toshiyuki
- Abstract
Expression of the gut-homing receptor integrin αEβ7, but not cutaneous lymphocyte-associated antigen (CLA), on milk allergen-stimulated cord blood T lymphocytes precedes the development of milk-induced eczema in early infancy. The data indicate the involvement of integrin αEβ7 in the development of infantile allergic eczema and provide a clue to the avoidance of specific allergens and novel therapy targeting homing receptors in food allergy.Copyright © 2001 S. Karger AG, Basel
- Subjects
CORD blood; T cells; ATOPIC dermatitis; SKIN inflammation; NEONATAL diseases
- Publication
International Archives of Allergy & Immunology, 2001, Vol 124, Issue 1-3, p332
- ISSN
1018-2438
- Publication type
Article
- DOI
10.1159/000053749