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- Title
Osteoporosis: An Unusual Presentation of Childhood Crohn’s Disease.
- Authors
THEARLE, M.; HORLICK, M.; BILEZIKIAN, J. P.; LEVY, J.; GERTNER, J. M.; LEVINE, L. S.; HARBISON, M.; BERDON, W.; OBERFIELD, S. E.
- Abstract
Osteoporosis is known to be associated with Crohn’s disease. We report a 12-yr-old boy without a history of steroid use, in whom severe osteoporosis and multiple collapsed vertebrae were the presenting manifestations of Crohn’s disease. After treatment of the Crohn’s disease, he resumed normal growth and progressed through puberty. Concomitantly, he demonstrated a substantial recovery of vertebral bone mineral density and structure. Possible pathophysiological mechanisms underlying the osteoporosis and the subsequent improvement in bone density are discussed.
- Publication
Journal of Clinical Endocrinology & Metabolism, 2000, Vol 85, Issue 6, p2122
- ISSN
0021-972X
- Publication type
Article
- DOI
10.1210/jc.85.6.2122