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- Title
Polydopamine-Assisted Electrochemical Fabrication of Polypyrrole Nanofibers on Bone Implants to Improve Bioactivity.
- Authors
Wang, Zhengao; Zhou, Lei; Yu, Peng; Liu, Yan; Chen, Junqi; Liao, Jingwen; Li, Weiping; Chen, Wei; Zhou, Wenhao; Yi, Xin; Ouyang, Kongyou; Zhou, Zhengnan; Tan, Guoxin; Ning, Chengyun
- Abstract
Dopamine is a molecule that facilitates biomineralization, and it is used to prepare electropolymerization-induced polydopamine (PDA). For the first time, dopamine is used for template-free electrochemical polymerization to form biocompatible polypyrrole (PPy) nanofiber coatings on bone implants. Dopamine monomers are electropolymerized to PDA chains affixed to biomedical titanium after the nanomicelles are tuned to self-assemble by triggering the potential, resulting in nanofiber formation. Dopamine serves as a dopant to induce the formation of conductive PPy nanofibers and as a promoter to accelerate biomineralization, cell proliferation, and adhesion.
- Subjects
NANOSTRUCTURED materials synthesis; NANOFIBERS; POLYPYRROLE; ELECTROPOLYMERIZATION; ARTIFICIAL bones; NANOFABRICATION; OSSEOINTEGRATION; DOPAMINE; MOLECULAR self-assembly
- Publication
Macromolecular Materials & Engineering, 2016, Vol 301, Issue 11, p1288
- ISSN
1438-7492
- Publication type
Article
- DOI
10.1002/mame.201600285