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- Title
Long-term neuroimaging follow-up of COVID-19-related leukoencephalopathy.
- Authors
Lang, Min; Chang, Yuh-Shin; Mehan Jr, William A.; Rincon, Sandra P.; Buch, Karen
- Abstract
More than a year after the start of the COVID-19 pandemic, long-term neurological manifestations of COVID-19 are increasingly being reported. The long-term sequelae of COVID-19-related leukoencephalopathy, however, remain unclear. Here, we present long-term neuroimaging follow-up in two cases of COVID-19-related leukoencephalopathy. The two cases demonstrate the utility of brain MRI for evaluating neurologic symptoms in critically ill patients with COVID-19, for diagnosis of underlying neural injury and prognostication of future recovery. The presence of leukoencephalopathy may result in chronic neurologic manifestations and may represent a poor prognosticator of neurologic recovery. The presence of leukoencephalomalacia on follow-up neuroimaging is potentially an indicator of irreversible white matter damage, which may be associated with more severe chronic deficits.
- Subjects
PATIENT aftercare; COVID-19; BRAIN diseases; MAGNETIC resonance imaging; NEURORADIOLOGY
- Publication
Neuroradiology, 2021, Vol 63, Issue 12, p2153
- ISSN
0028-3940
- Publication type
Article
- DOI
10.1007/s00234-021-02829-1