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- Title
Connecting membrane traffic to ESCRT and the final cut.
- Authors
Echard, Arnaud
- Abstract
The ESCRT (endosomal sorting complex required for transport) machinery is responsible for scission of the cytokinetic bridge that connects daughter cells at the end of mitosis. Specific endosomes are now found to mediate local bridge constriction and actin clearance in human cells, which contribute to the recruitment of ESCRT components at the abscission site.
- Subjects
SCISSION (Chemistry); MITOSIS; ENDOSOMES; CYTOKINESIS; ACTIN; HUMAN cell membranes
- Publication
Nature Cell Biology, 2012, Vol 14, Issue 10, p983
- ISSN
1465-7392
- Publication type
Article
- DOI
10.1038/ncb2598