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- Title
T-lymphocytes in bone marrow samples of children with acute lymphoblastic leukemia during and after chemotherapy might hamper PCR-based minimal residual disease studies.
- Authors
van Wering, E R; van der Linden-Schrever, B E M; van der Velden, V H J; Szczepański, T; van Dongen, J J M; van der Linden-Schrever, B E; van der Velden, V H; Szczepański, T; van Dongen, J J
- Abstract
Discusses the role of T-lymphocytes in bone marrow (BM) samples of acute lymphoblastic leukemia children in hampering polymerase chain reaction-based minimal residual disease studies. Observance of T-lymphocyte frequencies during and after chemotherapy; Number of TCRG gene rearrangements evaluated; Comparison of BM samples obtained from the children with normal BM samples.
- Subjects
T cells; LYMPHOBLASTIC leukemia in children; ANTINEOPLASTIC agents; CARCINOGENESIS; BONE marrow; LYMPHOBLASTIC leukemia; POLYMERASE chain reaction
- Publication
Leukemia (08876924), 2001, Vol 15, Issue 8, p1301
- ISSN
0887-6924
- Publication type
commentary
- DOI
10.1038/sj.leu.2402184