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- Title
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
- Authors
Zimmer, Sebastian; Grebe, Alena; Bakke, Siril S.; Bode, Niklas; Halvorsen, Bente; Ulas, Thomas; Skjelland, Mona; De Nardo, Dominic; Labzin, Larisa I.; Kerksiek, Anja; Hempel, Chris; Heneka, Michael T.; Hawxhurst, Victoria; Fitzgerald, Michael L.; Trebicka, Jonel; Björkhem, Ingemar; Gustafsson, Jan-Åke; Westerterp, Marit; Tall, Alan R.; Wright, Samuel D.
- Abstract
The article presents research on the promotion of atherosclerosis regression by cyclodextrin through macrophage reprogramming. Topics discussed include the association of atherosclerosis with elevated blood cholesterol concentrations, the deposition of cholesterol crystals, and the safe treatment of cyclodextrin.
- Subjects
ATHEROSCLEROSIS treatment; CYCLODEXTRINS synthesis; ATHEROSCLEROSIS prevention; BLOOD cholesterol; CARDIOVASCULAR diseases risk factors; THERAPEUTICS
- Publication
Science Translational Medicine, 2016, Vol 8, Issue 333, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aad6100