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- Title
Sodium channel Na<sub>x</sub> is a regulator in epithelial sodium homeostasis.
- Authors
Wei Xu; Seok Jong Hong; Aimei Zhong; Ping Xie; Shengxian Jia; Zhong Xie; Zeitchek, Michael; Niknam-Bienia, Solmaz; Jingling Zhao; Porterfield, D. Marshall; Surmeier, D. James; Leung, Kai P.; Galiano, Robert D.; Mustoe, Thomas A.
- Abstract
The article discusses a study focusing on the sodium channel Na(x) and its role in regulating epithelial sodium homeostasis. Topics discussed include the response of the epidermis to disturbances in barrier function, the up-regulation of prostasin by Na(x), and the increased downstream messenger RNA (mRNA) synthesis of inflammatory mediators.
- Subjects
SODIUM channels; EPITHELIUM; HOMEOSTASIS; EPIDERMIS; PROSTASIN; MESSENGER RNA
- Publication
Science Translational Medicine, 2015, Vol 7, Issue 312, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aad0286