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- Title
Working stiff: How obesity boosts cancer risk.
- Authors
Arendt, Lisa M.; Kuperwasser, Charlotte
- Abstract
The article offers information on a study concerning the role of obesity in promoting cancer progression and metastasis by altering the biomechanical microenvironment of fatty adipose tissue in the breast. Topics discussed include modification of extracellular matrix (ECM) for reflecting the physiological state of the adjacent tissue; and risks associated with breast cancer.
- Subjects
OBESITY; CANCER invasiveness; METASTASIS; BREAST cancer; ADIPOSE tissues; EXTRACELLULAR matrix
- Publication
Science Translational Medicine, 2015, Vol 7, Issue 301, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aac9446