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- Title
Ultrasound‐Guided Core Needle Biopsy of Non‐Palpable Breast Lesions: a Prospective Analysis in 204 Cases.
- Authors
Vega BolÍvar, A.; Alonso-Bartolomé, P.; Ortega GarcÍa, E.; Garijo Ayensa, F.
- Abstract
Purpose: To assess the diagnostic value of ultrasound (US)‐guided 14 G core needle breast biopsy in non‐palpable suspicious breast lesions. Material and Methods: From August 1997 to April 2001, 198 patients with 204 suspicious non‐palpable breast lesions underwent US‐guided large core needle biopsy. Biopsies were performed with a free‐hand technique using US equipment with a 7.5 MHz linear‐array transducer; a minimum of three cores were obtained from each lesion. Pathological findings in US‐guided core biopsy were correlated to findings in subsequent surgery or long‐term (more than 2 years) imaging follow‐up. Results: Among the 204 non‐palpable breast lesions for which histopathological findings were obtained by US‐guided core biopsy, 118 were malignant (114 carcinoma, 2 metastasis, 1 lymphoma, and 1 malignant phyllodes tumor) and 86 were benign (4 carcinoma and 82 benign lesions confirmed at surgery or after at least 2 years of follow‐up). Sensitivity, specificity, positive predictive value, and negative predictive value for diagnosis of malignancy in our series were 97%, 100%, 100%, and 95%, respectively. Diagnostic yield with 1, 2, 3, and 4 specimens per lesion was 73.5%, 88%, 94%, and 97.5%, respectively. Conclusion: US‐guided core needle biopsy is a sensitive percutaneous biopsy method for diagnosing non‐palpable breast lesions. To achieve a high diagnostic yield, a minimum number of three cores per lesion is advisable.
- Subjects
NEEDLE biopsy; BIOPSY; BREAST cancer diagnosis; CANCER in women; CANCER diagnosis; ULTRASONIC imaging; MEDICAL imaging systems; DIAGNOSIS
- Publication
Acta Radiologica, 2005, Vol 46, Issue 7, p690
- ISSN
0284-1851
- Publication type
Article
- DOI
10.1080/02841850500225740