We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Different Mid-Term Prognostic Predictors of Major Adverse Events in Diabetic and Nondiabetic Peripheral Artery Disease Presenting With Critical Limb Ischemia.
- Authors
Liang, Kae-Woei; Kuo, Hsun-Nan; Lee, Wen-Lieng; Liu, Tsun-Jui; Lin, Wei-Wen; Tsao, Chen-Rong; Ting, Chih-Tai; Wang, Kuo-Yang
- Abstract
We compared midterm prognostic predictors of peripheral artery disease (PAD) with or without diabetes mellitus (DM) presenting with critical lower limb ischemia (CLI). A total of 172 patients with PAD (109 DM; 63 non-DM) were enrolled. The major adverse events (MAEs) were death or amputation. The diabetic group had a higher MAE rate (39% vs 22%, P = .042) with a mean follow-up duration of 30 ± 19 months. In a multivariate binary logistic regression analysis, revascularization (odds ratio = 0.289, P = .006) and higher serum cholesterol (odds ratio=0.988, P = .027) predicted a lower MAE rate in the DM group. In contrast, the presence of severe chronic kidney disease (stage 4 or 5, odds ratio = 5.238, P = .025) was a positive predictor of MAEs in the nondiabetic group. In conclusion, the prognostic predictors of MAE in diabetic and nondiabetic patients with PAD and CLI were different.
- Subjects
DIABETES complications; KIDNEY disease diagnosis; CHRONIC kidney failure complications; AMPUTATION; CHOLESTEROL; CONFIDENCE intervals; FISHER exact test; GLOMERULAR filtration rate; ISCHEMIA; LEG; MORTALITY; PERIPHERAL vascular diseases; RESEARCH funding; STATISTICS; T-test (Statistics); DATA analysis; MULTIPLE regression analysis; CONTRAST media; RETROSPECTIVE studies; REVASCULARIZATION (Surgery); DATA analysis software; DESCRIPTIVE statistics; ODDS ratio; MANN Whitney U Test; DISEASE complications; PROGNOSIS
- Publication
Angiology, 2016, Vol 67, Issue 3, p287
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/0003319712475074