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- Title
A physical map of human chromosome 14.
- Authors
Bruls, Thomas; Gyapay, Gabor; Petit, Jean-Louis; Artiguenave, Francois; Vico, Virginie; Qin, Shizen; Tin-Wollam, Aye Mon; Da Silva, Corinne; Muselet, Delphine; Mavel, Delphine; Pelletier, Eric; Levy, Michael; Fujiyama, Asao; Matsuda, Fumihiko; Wilson, Richard; Rowen, Lee; Hood, Leroy; Weissenbach, Jean; Saurin, William; Heilig, Roland
- Abstract
Reports the construction of a tiling path of around 650 clones covering more than ninety-nine percent of human chromosome 14. Clone overlap information which was derived by comparing fully sequenced clones with a database of clone end sequences; Selection of homogeneously distributed seed points using an auxiliary high-resolution radiation hybrid map; Long-range continuity and low redundancy of the tiling path, which indicates that the method compares favorably with alternative gene mapping techniques.
- Subjects
HUMAN chromosomes; GENE mapping; GENETIC techniques; CLONING
- Publication
Nature, 2001, Vol 409, Issue 6822, p947
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/35057177