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- Title
Elastin is an essential determinant of arterial morphogenesis.
- Authors
Li, Dean Y.; Brooke, Benjamin; Davis, Elaine C.; Mecham, Robert P.; Sorensen, Lise K.; Boak, Beth B.; Eichwald, Ernst; Keating, Mark T.
- Abstract
Presents research which defined the role of elastin in arterial development and disease by generating mice that lack elastin. Previous thoughts about elastin's role; How the generated mice die; Developments similar to atherosclerosis; Traits of mice; Disruption of elastin and obstructive arterial disease; Elastin's regulatory function during arterial development.
- Subjects
ELASTIN; ARTERIES; ATHEROSCLEROSIS; ANIMAL models in research; CYTOCHEMISTRY
- Publication
Nature, 1998, Vol 393, Issue 6682, p276
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/30522