We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Prevalence and Risk of Dental Erosion in Patients with Gastroesophageal Reflux Disease: A Meta-Analysis.
- Authors
Yanushevich, Oleg O.; Maev, Igor V.; Krikheli, Natella I.; Andreev, Dmitrii N.; Lyamina, Svetlana V.; Sokolov, Filipp S.; Bychkova, Marina N.; Beliy, Petr A.; Zaslavskaya, Kira Y.
- Abstract
Aim: The present paper aims to systematize data concerning the prevalence and risk of dental erosion (DE) in adult patients with gastroesophageal reflux disease (GERD) compared to controls. Materials and methods: Core electronic databases, i.e., MEDLINE/PubMed, EMBASE, Cochrane, Google Scholar, and the Russian Science Citation Index (RSCI), were searched for studies assessing the prevalence and risk of DE in adult GERD patients with publication dates ranging from 1 January 1985 to 20 January 2022. Publications with detailed descriptive statistics (the total sample size of patients with GERD, the total sample size of controls (if available), the number of patients with DE in the sample of GERD patients, the number of patients with DE in the controls (if available)) were selected for the final analysis. Results: The final analysis included 28 studies involving 4379 people (2309 GERD patients and 2070 control subjects). The pooled prevalence of DE was 51.524% (95 CI: 39.742–63.221) in GERD patients and 21.351% (95 CI: 9.234–36.807) in controls. An association was found between the presence of DE and GERD using the random-effects model (OR 5.000, 95% CI: 2.995–8.345; I2 = 79.78%) compared with controls. When analyzing studies that only used validated instrumental methods for diagnosing GERD, alongside validated DE criteria (studies that did not specify the methodologies used were excluded), a significant association between the presence of DE and GERD was revealed (OR 5.586, 95% CI: 2.311–13.503; I2 = 85.14%). Conclusion: The meta-analysis demonstrated that DE is quite often associated with GERD and is observed in about half of patients with this extremely common disease of the upper gastrointestinal tract.
- Subjects
TOOTH erosion; GASTROESOPHAGEAL reflux; GASTROINTESTINAL diseases; CORE materials
- Publication
Dentistry Journal, 2022, Vol 10, Issue 7, pN.PAG
- ISSN
2304-6767
- Publication type
Article
- DOI
10.3390/dj10070126